Sitova 20 mg (Tablet)

Unit Price: ৳ 19.00 (2 x 10: ৳ 380.00)
Strip Price: ৳ 190.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Silco pharmaceutical ltd
Also available as
Sitova 10 mg tablet

Title

Sitova 20 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals

Description

Sitova is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in various diseases.

DosageAndAdministration

  • Adults: Usually 10 mg once daily; max. 80 mg once daily.
  • Child (10-18 years): Initially 10 mg once daily, increased if necessary at intervals of at least 4 weeks to usual max. 20 mg once daily.

Indications

  • Reduction of total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia.
  • Reduction of elevated cholesterol and triglycerides in patient with mixed dyslipidemia (Fredrickson Type Ia and Ib).
  • Treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia (Fredrickson Type IV).
  • Treatment of patients with dysbetalipoproteinaemia (Fredrickson Type III).
  • Reduction of cardiac ischaemic events in patients with asymptomatic or mild to moderate symptomatic coronary artery disease with elevated LDL-cholesterol level.

Pharmacology

  • Absorption: Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours.
  • Distribution: Mean volume of distribution is approximately 381 liters.
  • Metabolism: Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products.
  • Excretion: Eliminated primarily in bile following hepatic and/or extra-hepatic metabolism.

Interaction

  • Antacid: Plasma concentrations of atorvastatin decreased approximately 35% when coadministered with antacid suspension.
  • Colestipol: Plasma concentrations of atorvastatin decreased approximately 25% when coadministered with colestipol.

Contraindications

Hypersensitivity to any component of this medication. Active liver disease or unexplained persistent elevations of serum transaminases.

SideEffects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

PregnancyAndLactation

  • Pregnancy: Contraindicated during pregnancy. Safety in pregnant women has not been established.
  • Lactation: Not known whether atorvastatin or its metabolites are excreted in human milk. Contraindicated during breastfeeding.

PrecautionsAndWarnings

  • LiverEffects: Liver function tests should be performed before the initiation of treatment and periodically thereafter.
  • AlcoholConsumption: Use with caution in patients who consume substantial quantities of alcohol or have a history of liver disease.

SpecialPopulations

  • Geriatric: Plasma concentrations are higher in healthy elderly subjects than in young adults.
  • Gender: No clinically significant difference in LDL-C reduction with Sitova between men and women.
  • RenalInsufficiency: Renal disease has no influence on the plasma concentrations or LDL-C reduction of Sitova.

OverdoseEffects

Specific treatment is not available for atorvastatin overdose. Should be treated symptomatically and supportive measures instituted.

TherapeuticClass

Other Anti-anginal & Anti-ischaemic drugs, Statins

StorageConditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

ChemicalStructure

  • MolecularFormula: C33H35FN2O5
  • ChemicalStructureLink: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg

CommonlyAskedQuestions

  • What is Sitova 20 mg Tablet?
  • How should I take Sitova 20 mg Tablet?
  • What are the uses of Sitova 20 mg Tablet?
  • What are the Side Effects of Sitova 20 mg Tablet?
  • What are the instructions for storage and disposal Sitova 20 mg Tablet?
  • Is Sitova 20 mg Tablet used for lowering cholesterol?
  • Will taking Sitova 20 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Sitova 20 mg Tablet? Is it safe for long-term use?
  • Does Sitova 20 mg Tablet cause weight loss?
  • Can I stop taking Sitova 20 mg Tablet?
  • Does Sitova 20 mg Tablet cause memory loss?
  • Does Sitova 20 mg Tablet make you tired?
  • Can Sitova 20 mg Tablet be prescribed to children?
  • Is Sitova 20 mg Tablet a blood thinner?

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