Cilosta 100 mg (Tablet)

Unit Price: ৳ 12.09 (3 x 10: ৳ 362.70)
Strip Price: ৳ 120.90

Medicine Details

Category Details
Generic Cilostazol
Company Square pharmaceuticals plc

Indications

  • Reduction of symptoms of intermittent claudication
  • Increased walking distance

Pharmacology

  • Cilostazol is a quinolinone derivative
  • Inhibits cellular phosphodiesterase III (PDE III)
  • Suppresses cAMP degradation
  • Increases cAMP in platelets and blood vessels
  • Inhibits platelet aggregation
  • Causes vasodilation

Dosage & Administration

  • Recommended dosage: 100 mg bid
  • Should be taken at least half an hour before or two hours after meals
  • Consider 50 mg bid dosage during coadministration with certain drugs

Interaction

  • Omeprazole and Erythromycin increased systemic exposure of Cilosta
  • Higher concentrations of Cilosta with concurrent Diltiazem treatment

Contraindications

  • Patients with congestive heart failure
  • Patients with known or suspected hypersensitivity to any components

Side Effects

  • Common: headache, diarrhoea, vomiting, leg cramps, rash
  • Less frequent: anorexia, edema

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Transfer of Cilostazol into milk reported in experimental animals
  • Potential risk to nursing infants

Precautions & Warnings

  • Use with caution in patients with any degree of heart failure
  • No information on concurrent use with Clopidogrel

Therapeutic Class

  • Peripheral Vasodilator drugs: Intermittent Claudication

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

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