Terbixen 250 mg (Tablet)
Unit Price: ৳ 60.00 (1 x 10: ৳ 600.00)
Strip Price: ৳ 600.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Everest pharmaceuticals ltd |
Title
- Terbixen Products
Categories
- Medicine
- Pharmacy
- Healthcare
Description
- Antifungal tablet for onychomycosis
- Granules for Tinea Capitis
- Cream for fungal infections of the skin
- 1% Spray for tinea infections and pityriasis versicolor
- Inhibitor of CYP450 2D6 isozyme
- Contraindicated for individuals hypersensitive to terbinafine
- Adverse events include gastrointestinal symptoms, liver test abnormalities, rashes, and taste disturbances
- Not recommended during pregnancy or lactation
- Rare cases of liver failure reported
- Limited clinical experience with pediatric patients
- Safe storage below 30°C and protection from light
Dimensions
Varies by product
Color Options
N/A
Functions
- Treatment of onychomycosis
- Inhibition of CYP450 2D6 isozyme
- Fungicidal effect against Tricophyton Mentagrophyte and Trichophyton Rubrum
Materials
Terbinafine
Technical Specifications
- Tablet: 250mg terbinafine
- Granules: Doses based on body weight
- Dosage: Varies by indication
- Cream: Applied once or twice daily
- 1% Spray: Applied once or twice daily
Design Elements
N/A
Usability Features
- Optimal clinical effect observed after mycological cure and cessation of treatment
- Dosage varies for fingernail and toenail onychomycosis
- Relief of clinical symptoms usually occurs within a few days
Dosage & Administration
- Terbinafine tablet:
- For fingernail onychomycosis: 250mg once daily for 6 weeks
- For toenail onychomycosis: 250mg once daily for 12 weeks
- Terbinafine granules:
- <25 kg: 125mg/day up to 6 weeks
- 25-35 kg: 187.5mg/day up to 6 weeks
- >35 kg: 250mg/day up to 6 weeks
- Terbinafine cream: Applied once or twice daily as per indication
- Terbinafine 1% Spray: Applied once or twice daily depending on the indication
Interaction
Inhibitor of CYP450 2D6 isozyme
Contraindications
Hypersensitivity to terbinafine
Side Effects
- Gastrointestinal:
- Diarrhea
- Dyspepsia
- Abdominal pain
- Other Adverse Reactions:
- Liver test abnormalities
- Rashes
- Urticaria
- Pruritus
- Taste disturbances
- Serious skin reactions
- Severe neutropenia
- Thrombocytopenia
- Angioedema
- Allergic reactions
Pregnancy & Lactation
- Terbinafine tablet: Not recommended during pregnancy or lactation
- Terbinafine cream: Not recommended unless potential benefits outweigh risks
Precautions & Warnings
- Warnings:
- Rare cases of liver failure
- Serious skin reactions
- Precautions:
- Not recommended for patients with chronic or active liver disease
- Pretreatment serum transaminase tests advised
Use in Special Populations
- Pediatric use: Safety and efficacy not established
- Use in the elderly: No evidence of different dosages or side-effects
Overdose Effects
Limited clinical experience, symptoms include nausea, vomiting, abdominal pain
Therapeutic Class
- Antifungal preparations
- Topical Antifungal preparations
Storage Conditions
Cool, dry place below 30°C, protect from light