Alphalok XR 2.5 mg (Tablet (Extended Release))
Unit Price: ৳ 10.00 (2 x 14: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Prazosin hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Hypertension
- Left Ventricular Failure
- Raynaud's Phenomenon
- Raynaud's Disease
- Benign Prostatic Hyperplasia
Pharmacology
- Selective inhibition of alpha-1-adrenoreceptors
- Reduction in total peripheral vascular resistance
- Reduction in left ventricular filling pressure
- Reduction in cardiac impedance
- Augmentation of cardiac output
Dosage & Administration
- Adjustable dosage based on patient's response
- Use with diuretic and/or other antihypertensive drugs
- Initial low starting dose for best toleration
Interaction
- No adverse drug interaction observed in clinical experience to date
- Not reported to interact adversely with common medication classes
Contraindications
- Known sensitivity to quinazolines
Side Effects
- Dizziness
- Headache
- Drowsiness
- Weakness
- Palpitations
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort
- Liver function abnormalities
- Pancreatitis
- Edema
- Orthostatic hypotension
- Dyspnea
- Faintness
- Tachycardia
- Nervousness
- Vertigo
- Hallucinations
- Depression
- Rash
- Pruritus
- Alopecia
Pregnancy & Lactation
- No teratogenic effects seen in animal testing
- Excretion in small amounts in human milk
- Caution in use during pregnancy and nursing
Precautions & Warnings
- Postural hypotension risk at initial dose
- Gradual titration is important to prevent fluid retention
- Monitoring blood pressure during administration and adjustment of dose
Use in Special Populations
- Not recommended for children under 12 years
- Not recommended for left ventricular failure due to mechanical obstruction
- Efficacy not established for left ventricular failure due to recent myocardial infarction
Overdose Effects
- Profound drowsiness and depressed reflexes observed
- No decrease in blood pressure noted in case of accidental ingestion by a child
- Cardiovascular system support of first importance in case of hypotension
Therapeutic Class
- Alpha adrenoceptor blocking drugs
Storage Conditions
- Keep away from light and moisture
- Store below 30°C
- Keep out of reach of children