Nitrobac 100 mg (Capsule (Sustained Release))

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Nitrofurantoin
Company Ibn sina pharmaceuticals ltd
Also available as
Nitrobac 25 mg suspension

Indications

  • Treatment of urinary tract infections
  • Prophylaxis of urinary tract infections
  • Affected bacterial strains include Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus, Klebsiella species, Enterobacter species
  • Active against Gram-Positive Aerobes and Gram-Negative Aerobes

Pharmacology

  • Antibacterial agent specific for urinary tract infections
  • Highly soluble in urine and may impart a brown color to it
  • Inactivates or alters bacterial ribosomal proteins and macromolecules
  • Active against specific bacteria strains

Dosage

  • Dosage information for nitrofurantoin tablets, capsules, SR capsules, and suspension in adults and children
  • Different dosage levels for uncomplicated urinary tract infections, long-term suppressive therapy, acute uncomplicated UTIs, prophylaxis, and genito-urinary surgical prophylaxis
  • Dosage reduction for long-term suppression in adults
  • Specific dosage recommendations for pediatric patients

Administration

  • Should be taken with food

Interaction

  • Interactions with antacids containing Magnesium Trisilicate
  • Impact on the absorption of uricosuric drugs
  • Inhibition of renal tubular secretion

Contraindications

  • Anuria, oliguria, or significant impairment of renal function
  • Contraindicated in pregnant patients at 38-42 weeks, during labor and delivery
  • Known hypersensitivity to Nitrofurantoin

Side Effects

  • Frequent clinical adverse events: nausea, headache, flatulence
  • Less common adverse events: diarrhea, dyspepsia, abdominal pain, constipation, emesis, dizziness, drowsiness

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Detection in human breast milk in trace amounts
  • Importance of the drug to the mother vs. potential adverse reactions in nursing infants

Precautions & Warnings

  • Discontinue if acute, sub-acute, or chronic pulmonary reactions occur
  • Avoid taking Antacid preparations containing magnesium trisilicate

Overdose Effects

  • Occasional incidents of acute overdosage
  • Recommendation for induction of emesis

Therapeutic Class

  • Systemic Urinary Anti-infective

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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