Nitrobac 100 mg (Capsule (Sustained Release))
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Nitrofurantoin |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Treatment of urinary tract infections
- Prophylaxis of urinary tract infections
- Affected bacterial strains include Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus, Klebsiella species, Enterobacter species
- Active against Gram-Positive Aerobes and Gram-Negative Aerobes
Pharmacology
- Antibacterial agent specific for urinary tract infections
- Highly soluble in urine and may impart a brown color to it
- Inactivates or alters bacterial ribosomal proteins and macromolecules
- Active against specific bacteria strains
Dosage
- Dosage information for nitrofurantoin tablets, capsules, SR capsules, and suspension in adults and children
- Different dosage levels for uncomplicated urinary tract infections, long-term suppressive therapy, acute uncomplicated UTIs, prophylaxis, and genito-urinary surgical prophylaxis
- Dosage reduction for long-term suppression in adults
- Specific dosage recommendations for pediatric patients
Administration
- Should be taken with food
Interaction
- Interactions with antacids containing Magnesium Trisilicate
- Impact on the absorption of uricosuric drugs
- Inhibition of renal tubular secretion
Contraindications
- Anuria, oliguria, or significant impairment of renal function
- Contraindicated in pregnant patients at 38-42 weeks, during labor and delivery
- Known hypersensitivity to Nitrofurantoin
Side Effects
- Frequent clinical adverse events: nausea, headache, flatulence
- Less common adverse events: diarrhea, dyspepsia, abdominal pain, constipation, emesis, dizziness, drowsiness
Pregnancy & Lactation
- Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Detection in human breast milk in trace amounts
- Importance of the drug to the mother vs. potential adverse reactions in nursing infants
Precautions & Warnings
- Discontinue if acute, sub-acute, or chronic pulmonary reactions occur
- Avoid taking Antacid preparations containing magnesium trisilicate
Overdose Effects
- Occasional incidents of acute overdosage
- Recommendation for induction of emesis
Therapeutic Class
- Systemic Urinary Anti-infective
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children
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