Urinom D 0.4 mg+0.5 mg (Capsule)

Unit Price: ৳ 20.00 (3 x 6: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Tamsulosin hydrochloride dutasteride
Company Opsonin pharma ltd

Therapeutic Class

  • BPH/ Urinary retention/ Urinary incontinence

Indications

  • Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH)
  • Reduction in the risk of acute urinary retention and surgery in patients with moderate to severe symptoms of BPH

Pharmacology

  • Combination of Tamsulosin Hydrochloride and Dutasteride
  • Mechanisms of action to improve symptoms in patients with BPH

Dosage & Administration

  • Recommended dose is one capsule (Tamsulosin Hydrochloride 0.4 mg & Dutasteride 0.5 mg) taken orally approximately 30 minutes after the same meal each day
  • Capsules should be swallowed whole and not chewed or opened
  • May be used to substitute concomitant Tamsulosin Hydrochloride and Dutasteride in existing dual therapy
  • No adjustment in dosage is anticipated for patients with renal impairment
  • Caution should be used in patients with mild to moderate hepatic impairment
  • Contra-indicated in patients with severe hepatic impairment

Interaction

  • No drug interaction studies for Dutasteride-Tamsulosin combination
  • Effects of other drugs on the pharmacokinetics of Dutasteride
  • Effects of Dutasteride on the pharmacokinetics of other drugs

Contraindications

  • Contra-indicated in women and children and adolescents
  • Patients with hypersensitivity to Dutasteride, other 5-alpha reductase inhibitors, or Tamsulosin
  • Contra-indicated in patients with a history of orthostatic hypotension and severe hepatic impairment

Side Effects

  • Most common adverse reactions include impotence, decreased libido, breast disorders, ejaculation disorders, and dizziness

Pregnancy & Lactation

  • Contra-indicated for use by women
  • No studies available regarding the effect on pregnancy, lactation, and fertility

Precautions & Warnings

  • Prescribed after careful benefit-risk assessment
  • Caution for potential increased risk of adverse events
  • Effects on prostate specific antigen (PSA) and prostate cancer detection
  • Regular evaluation for prostate cancer risk including PSA testing
  • Caution for renal impairment, hypotension, and Intraoperative Floppy Iris Syndrome
  • Avoid contact with leaking capsules
  • Caution in the administration of Tamsulosin-Dutasteride to patients with mild to moderate hepatic impairment

Overdose Effects

  • No data available for overdose of Tamsulosin-Dutasteride combination
  • Single daily doses of Dutasteride up to 40 mg/day have been administered for 7 days without significant safety concerns
  • Acute overdose with Tamsulosin Hydrochloride has been reported

Storage Conditions

  • Store in a cool and dry place, protected from light

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