Volifen 1% v/v (Topical Spray)

60 ml bottle: ৳ 250.00

Medicine Details

Indications

  • Rheumatology
  • Surgery and Traumatology
  • Obstetrics and Gynecology
  • Otorhinolaryngology
  • Dentistry
  • Urogenital Tract
  • Renal and Biliary Colic
  • Inflammatory forms of rheumatism
  • Degenerative forms of rheumatism
  • Chronic involutive
  • Polyarthritis
  • Ankylosing spondylarthritis
  • Osteoarthritis
  • Spondylarthroses
  • Acute gout
  • Peri-articular rheumatic disorders
  • Sprain
  • Bruises
  • Dislocations
  • Fractures
  • Soft tissue injuries
  • Surgical interventions
  • Primary dysmenorrhoea
  • Episiotomy
  • Adnexitis
  • Endometritis
  • Parametritis
  • Salpingitis
  • Mastitis
  • Pre-operative medication for the prevention of pain
  • Inflammation and swelling
  • Post-operative and post-traumatic pain
  • Inflammation and swelling (dentistry)

Pharmacology

  • Non-steroidal anti-inflammatory drug
  • Anti-rheumatic properties
  • Analgesic properties
  • Antipyretic properties
  • Uricosuric effect
  • Inhibition of prostaglandin biosynthesis
  • Rapid and complete absorption from the gastro-intestinal tract
  • Metabolism in the liver

Dosage & Administration

  • 75-150 mg daily in 2 to 3 divided doses for adults
  • 1 tablet daily for adults (Diclofenac SR)
  • 1-3 mg of diclofenac/kg body weight daily for children
  • Lowest effective dosage for elderly patients
  • 2-3 tablets daily for adults (Diclofenac Dispersible Tablet)
  • 1-3 mg/kg body weight for children (juveniles)
  • 1 capsule daily (Diclofenac TR Capsule)
  • 50 mg suppository 2-3 times daily for adults
  • External application: 2-4 g 3-4 times daily (Diclofenac Gel)

Interaction

  • Plasma concentration increase with lithium and digoxin
  • Increased risk of hemorrhage with anticoagulants
  • No influence on antidiabetic agents
  • Nephrotoxicity with cyclosporin
  • Serious toxicity with methotrexate
  • Convulsions due to interaction with quinolone antimicrobials

Contraindications

  • Hypersensitivity to any ingredient
  • Peptic ulcer
  • Hypersensitivity to Diclofenac or other NSAIDs
  • Asthmatic patients with known triggers

Side Effects

  • Mild, rare, and transient adverse effects
  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions (rash, eczema)

Pregnancy & Lactation

  • Use only for compelling reasons during pregnancy
  • Lowest effective dose during pregnancy
  • Not recommended during the first trimester
  • Insignificant quantity detected in breast milk
  • No expected undesirable effects on the infant

Precautions & Warnings

  • Close observation for peptic ulceration or gastrointestinal bleeding
  • Close observation in advanced age patients
  • Avoid contact with eyes or mucus membranes
  • Hands should be washed properly after application

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Store below 30°C
  • Keep out of the reach of children

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