Rezor Plus 20 mg+12.5 mg (Tablet)

Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)

Strip Price: ৳ 100.00

Medicine Details

Category	Details
Generic	Olmesartan medoxomil hydrochlorothiazide
Company	Renata limited
Also available as	Rezor plus 40 mg tablet

Indications

Treatment of hypertension

Pharmacology

Angiotensin-II blocker
Thiazide diuretic
Vasoconstrictor inhibitor
Aldosterone secretion blocker

Dosage & Administration

Usual starting dose of 20/12.5 mg
Individualized dosing
Titration based on blood pressure response

Interaction

No significant drug interactions with Olmesartan Medoxomil reported
Interaction potential with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, corticosteroids, ACTH, and lithium for Hydrochlorothiazide

Contraindications

Hypersensitivity to any component of the product
Anuria
Hypersensitivity to sulfonamide-derived drugs

Side Effects

Nausea
Headache
Dizziness
Hyperuricemia
Upper respiratory tract infection
Urinary tract infection
Chest pain
Back pain
Peripheral edema
Abdominal pain
Dyspepsia
Gastroenteritis
Diarrhea

Pregnancy & Lactation

Safety and effectiveness not established
Drug discontinuation during pregnancy and lactation

Precautions & Warnings

Periodic determination of serum electrolytes
Potential for hypokalemia, hyponatremia, hypochloremic alkalosis
Hyperuricemia risk with thiazide therapy
Impaired renal function

Use in Special Populations

Renal impairment caution with creatinine clearance >30 ml/min
Loop diuretics preferred for severe renal impairment
No dosage adjustment necessary for hepatic impairment
Not recommended for pediatric use
Cautious dose selection for geriatric use

Overdose Effects

Manifestations of hypotension and tachycardia with Olmesartan
Electrolyte depletion and dehydration symptoms with Hydrochlorothiazide

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Cool and dry storage
Protection from light and moisture
Keep out of the reach of children

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