Sitacret 50 mg (Tablet)
Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sitagliptin |
| Company | Renata limited |
Indications
- Adjunct to diet and exercise for type 2 diabetes mellitus
- Not for use in type 1 diabetes
Pharmacology
- DPP-4 inhibitor
- Increases insulin release and decreases glucagon levels
- Regulates glucose homeostasis
Dosage & Administration
- Recommended dose of 50mg or 100mg once or twice daily
- Can be taken with or without food
Interaction
- No meaningful alterations in pharmacokinetics of certain drugs
- Slightly increases mean Digoxin concentration
Contraindications
- History of serious hypersensitivity reaction to sitagliptin
Side Effects
- Common adverse reactions include headache, upper respiratory tract infection, and nasopharyngitis
- Hypoglycemia risk in combination with sulfonylurea and insulin
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in lactating rats
- Caution advised in nursing women
Precautions & Warnings
- Prompt discontinuation if pancreatitis is suspected
- Dosage adjustment in renal insufficiency
- Risk of hypersensitivity reactions
Use in Special Populations
- Safety and effectiveness not established in pediatric patients under 18 years
- Dose adjustment and renal function assessment in elderly patients
Overdose Effects
- Limited experience with doses above 800 mg
- Supportive measures in event of overdose
- Modest dialyzability
Therapeutic Class
- Dipeptidyl Peptidase-4 (DPP-4) inhibitor
Storage Conditions
- Store below 25°C in a dry place away from light
- Keep out of reach of children
- Dispense only on prescription