Roxadex 6 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 36.00 (2 x 5: ৳ 360.00)

Medicine Details

Indications

  • Allergic states
  • Collagen disease
  • Dermatologic diseases
  • Endocrine disorders
  • Gastrointestinal diseases
  • Hematologic disorders
  • Neoplastic diseases
  • Nervous system
  • Ophthalmic diseases
  • Renal diseases
  • Respiratory diseases
  • Rheumatic disorders
  • Miscellaneous

Pharmacology

  • Decreases inflammation
  • Inhibits migration of leukocytes
  • Reversal of capillary permeability
  • Suppresses normal immune response

Dosage & Administration

  • Oral dosages for adults
  • Oral dosages for children
  • Short dexamethasone suppression test
  • Intravenous (IV) administration
  • Intramuscular (IM) administration
  • Local injection administration
  • Dilution with infusion fluid
  • Dosage for systemic therapy in adults
  • Recommended local therapy doses

Interaction

  • Enhanced potassium loss with diuretics
  • Impaired glucose tolerance with antidiabetics
  • Increased incidence of gastro-intestinal ulceration with non-steroidal anti-inflammatory drugs
  • Altered need for oral anti-coagulants
  • Less effectiveness with liver enzyme inducing drugs
  • Potential reduction in glucocorticoid dosage with salicylates
  • Impaired gastro-intestinal absorption with antacids

Contraindications

  • Gastric and duodenal ulcers
  • Systemic and ophthalmic fungal infections
  • Viral infections
  • Glaucoma
  • Hypersensitivity to corticosteroids

Side Effects

  • Endocrine and metabolic disturbances
  • Fluid and electrolyte disturbances
  • Musculo-skeletal effects
  • Gastro-intestinal effects
  • Dermatological effects
  • Central Nervous System effects
  • Ophthalmic effects
  • Immunosuppressive effects

Pregnancy & Lactation

  • Pregnancy Category C
  • Potential presence in breast milk
  • Advice against breastfeeding for mothers on high dosages

Precautions & Warnings

  • Use of lowest possible dose
  • Caution in cardio-renal patients
  • Minimization of drug-induced secondary adrenocortical insufficiency
  • Caution in gastrointestinal conditions
  • Consideration for patients at risk of osteoporosis
  • Monitoring for potential acute myopathy

Use in Special Populations

  • Titration to the lowest effective dose for pediatric patients

Overdose Effects

  • Supportive and symptomatic therapy

Storage Conditions

  • Tablet storage instructions
  • Injection storage instructions
  • Protection from light and moisture
  • Temperature requirements
  • Protection from freezing
  • Keep out of the reach of children

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