Telmitan Max 10 mg+40 mg (Tablet)

Unit Price: ৳ 14.00 (2 x 14: ৳ 392.00)
Strip Price: ৳ 196.00

Medicine Details

Indications

  • Treatment of hypertension
  • First-line therapy for patients likely to need multiple drugs to achieve blood pressure goals

Pharmacology

  • Combination of Telmisartan and Amiodipine
  • Telmisartan: Angiotensin II antagonist with effects on vasoconstriction and aldosterone synthesis
  • Amiodipine: Calcium-channel blocker with effects on peripheral vascular resistance and blood pressure reduction

Dosage & Administration

  • Initial dose: 40/5 mg once daily
  • Higher initial dose: 80/5 mg once daily for patients requiring larger blood pressure reductions
  • Add-on therapy for patients not adequately controlled with single agents
  • Replacement therapy for patients receiving separate tablets of amiodipine and telmisartan
  • Maximum recommended dose: 80/10 mg once daily

Interaction

  • No clinically significant interaction with acetaminophen, simvastatin, or ibuprofen
  • Safety with co-administration of thiazide diuretics, beta-blockers, and oral hypoglycemic drugs

Contraindications

  • Hypersensitivity to the product or its components
  • Pregnancy and lactation
  • Biliary obstructive disorders, severe hepatic impairment
  • Hypotension, cardiogenic shock, left ventricle outflow tract obstruction

Side Effects

  • Dizziness
  • Peripheral edema
  • Migraine
  • Bradycardia
  • Cough
  • Abdominal pain
  • Nausea
  • Myalgia
  • Erectile dysfunction
  • Fatigue

Pregnancy & Lactation

  • Pregnancy Categories C (first trimester) and D (second and third trimesters)
  • Potential adverse effects on nursing infants

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Correct volume or salt depletion before initiating therapy
  • Monitor for worsening heart failure
  • Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker

Use in Special Populations

  • Pediatric use not established
  • Initial therapy not recommended for patients 75 years old or with hepatic impairment

Overdose Effects

  • Telmisartan overdose: Symptoms of hypotension, dizziness, tachycardia
  • Amiodipine overdose: Excessive peripheral vasodilation with marked hypotension

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Protect from light and high humidity
  • Keep out of the reach of children

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