Telmitan Max 10 mg+40 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 14: ৳ 392.00)
Strip Price: ৳ 196.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate telmisartan |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Treatment of hypertension
- First-line therapy for patients likely to need multiple drugs to achieve blood pressure goals
Pharmacology
- Combination of Telmisartan and Amiodipine
- Telmisartan: Angiotensin II antagonist with effects on vasoconstriction and aldosterone synthesis
- Amiodipine: Calcium-channel blocker with effects on peripheral vascular resistance and blood pressure reduction
Dosage & Administration
- Initial dose: 40/5 mg once daily
- Higher initial dose: 80/5 mg once daily for patients requiring larger blood pressure reductions
- Add-on therapy for patients not adequately controlled with single agents
- Replacement therapy for patients receiving separate tablets of amiodipine and telmisartan
- Maximum recommended dose: 80/10 mg once daily
Interaction
- No clinically significant interaction with acetaminophen, simvastatin, or ibuprofen
- Safety with co-administration of thiazide diuretics, beta-blockers, and oral hypoglycemic drugs
Contraindications
- Hypersensitivity to the product or its components
- Pregnancy and lactation
- Biliary obstructive disorders, severe hepatic impairment
- Hypotension, cardiogenic shock, left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Bradycardia
- Cough
- Abdominal pain
- Nausea
- Myalgia
- Erectile dysfunction
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C (first trimester) and D (second and third trimesters)
- Potential adverse effects on nursing infants
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct volume or salt depletion before initiating therapy
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
Use in Special Populations
- Pediatric use not established
- Initial therapy not recommended for patients 75 years old or with hepatic impairment
Overdose Effects
- Telmisartan overdose: Symptoms of hypotension, dizziness, tachycardia
- Amiodipine overdose: Excessive peripheral vasodilation with marked hypotension
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children