Doribac 500 mg (Capsule)

Unit Price: ৳ 10.53 (7 x 4: ৳ 294.84)
Strip Price: ৳ 42.12

Medicine Details

Indications

  • Treatment of infections due to Gram-positive organisms
  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic agent for surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Resistance to hydrolysis by penicillinase
  • Bactericidal antibiotic
  • Inhibition of cell wall formation
  • Inhibition of peptidoglycan synthesis
  • Resistance to gastric acid

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Dosage doubling in severe infections
  • Parenteral administration
  • Intramuscular and intravenous injection doses
  • Dosing for children based on age

Administration

Oral doses should be administered 1 hour before meal

Interaction

Concurrent use may result in increased level of Doribac in blood

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • FDA Pregnancy Category B
  • Caution in use during pregnancy
  • Excretion in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Caution in patients with evidence of hepatic dysfunction
  • Caution in treatment of patients with allergic diathesis

Use in Special Populations

Reduction in dose or dose interval in severe renal failure

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

  • Intraarticular injection
  • Intrapleural injection
  • Inhalation by nebuliser with sterile water
  • Dissolution in lignocaine hydrochloride

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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