Doribac 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 60.18
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Concord pharmaceuticals ltd |
| Also available as |
Indications
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis treatment
- Enteritis treatment
- Endocarditis treatment
- Urinary tract infection treatment
- Meningitis treatment
- Septicaemia treatment
- Prophylactic use in surgery
Pharmacology
- Active against Gram-positive organisms
- Little activity against Gram-negative bacilli
- Inhibits formation of bacterial cell wall
- Bactericidal antibiotic
- Useful against penicillinase-producing staphylococci
- Interferes with peptidoglycan synthesis
Dosage
- Oral administration for adults: 250 mg four times daily
- Increased dosage for severe infections
- Parenteral administration for adults: 250 mg-1 g four times daily
- Dosage may be doubled in severe infections
- Different dosage for children
Administration
- Oral doses to be administered 1 hour before a meal
Interaction
- Concurrent use may result in increased blood levels of Doribac
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Common gastrointestinal side effects
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Caution advised during lactation
Precautions & Warnings
- Use with caution in patients with hepatic dysfunction
- Caution in allergic diathesis
Use in Special Populations
- Reduced dose in severe renal failure
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Administered via intraarticular injection
- Administered via intrapleural injection
- Administered via nebulizer
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children