Respidox 100 mg/5 ml (Syrup)
100 ml bottle: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Concord pharmaceuticals ltd |
| Also available as |
Product Title
- Respidox
Categories
- Bronchodilator
- Medication
- Therapeutic Class
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Novel bronchodilator
- Inhibition of phosphodiesterase 4
- Decreased affinities toward adenosine A1 and A2 receptors
- Inhibition of platelet activating factor (PAF)
- Inhibition of leukotriene production
Dosage & Administration
- 200 mg tablet for elderly
- 400 mg tablet for adults
- 10 ml syrup for children above 12 years
- 6-9 mg/kg body weight for children aged 6-12 years
- Special release (SR) tablet for specific dosages
Interaction
- Avoid concurrent administration with xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Exercise caution with sympathomimetic drugs
- Potential interactions with several drugs like erythromycin, TAO, lincomycin, etc.
- Possible increase in dosage with concurrent use of phenytoin, other anticonvulsants, or cigarette smoking
Contraindications
- Known hypersensitivity to doxophylline or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- Lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Insomnia
- Tachycardia
- Extrasystoles
- Tachypnea
- Rare cases of hyperglycemia or albuminuria
- Potential severe cardiac arrhythmias and tonic-clonic seizures in case of overdose
Pregnancy & Lactation
- Animal tests showing no interference with pre and postnatal growth
- Need for careful evaluation of risk-benefit ratio in pregnancy
- Contraindication during lactation
- No effects on ability to drive and use machines
Precautions & Warnings
- Factors affecting hepatic clearance
- Monitoring of blood levels in case of influencing factors
- Caution in patients with cardiac disease, hypertension, elderly, severe hypoxemia, hyperthyroidism, chronic corpulmonale, liver disease, peptic ulcer, renal impairment
- Special caution in patients with congestive heart failure
- No risk of addiction or dependence
Overdose Effects
- Potential severe cardiac arrhythmias
- Tonic-clonic seizures
- Need for discontinuation of treatment and potential resumption at lower doses under physician's discretion
- Symptomatic treatment in case of overdose
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- Use only on prescription of specialist physician