Xorest 1 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Everest pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Treatment of akinetic and myoclonic seizures
- Treatment of absence seizures (petit mal)
Pharmacology
- Exhibits anticonvulsive effects
- Exhibits sedative effects
- Exhibits muscle relaxing effects
- Exhibits anxiolytic effects
- Enhances GABAergic neurotransmission
Dosage & Administration
- Initial adult dose for seizure disorders not to exceed 1.5 mg/day
- Initial adult dose for panic disorder is 0.25 mg
- Pediatric dose based on body weight and age
- Injection dosage for infants, children, and adults
Interaction
- Does not alter the pharmacokinetics of phenytoin
- Does not alter the pharmacokinetics of carbamazepine
- Does not alter the pharmacokinetics of phenobarbital
Contraindications
- Patients with history of hypersensitivity to benzodiazepines
- Patients with clinical or biochemical evidence of significant liver disease
- Patients with acute narrow angle glaucoma
Side Effects
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Coma
- Tremor
- Vertigo
- Depression
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Risk of producing congenital malformations
- Possible teratogenic effects
- Advised only if potential benefits outweigh risks
- Active ingredient passes into maternal milk in small amounts
Precautions & Warnings
- May increase incidence of generalized tonic-clonic seizures
- Concomitant use with valproic acid may produce absence status
Use in Special Populations
- Caution required in pediatric use due to increased bronchial secretion
- Greater pharmacologic effects in geriatric patients
- Renal impairment does not affect pharmacokinetics
- Hepatic impairment affects plasma protein binding
Overdose Effects
- Symptoms include drowsiness, ataxia, and nystagmus
- May lead to areflexia, apnoea, hypotension, and coma
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Instructions for slow intravenous injection
- Instructions for intravenous infusion
- Instructions for intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
Common Questions about Xorest 1 mg Tablet
- Not used as a sleeping pill
- Need to be taken as advised by the doctor
- Common withdrawal symptoms
- Monitoring for early symptoms of suicidal thoughts and actions
- Potential to cause weight gain
- Does not affect memory
- Possible side effects of overdose
- Interactions with other medications