Fragmin 5000 IU/0.2 ml (SC Injection)

5000 IU pre-filled syringe: ৳ 412.00 (2 x 5: ৳ 4,120.00)

Medicine Details

Category Details
Generic Dalteparin sodium
Company Pfizer
Also available as

Indications

  • Prophylaxis of clotting in extracorporeal circulation in haemodialysis or haemofiltration
  • Unstable angina
  • Prophylaxis of venous thromboembolism during surgical procedures
  • Venous thromboembolism

Pharmacology

  • Antithrombotic agent
  • Potentiates the inhibition of factor Xa and thrombin by antithrombin

Dosage & Administration

  • Intravenous administration
  • Subcutaneous administration
  • Dosage based on specific indications and patient characteristics

Interaction

  • Increased risk of haemorrhage with other anticoagulant/antiplatelet agents
  • Reduced anticoagulant effect with certain medications

Contraindications

  • Hypersensitivity
  • Active major bleeding
  • Severe coagulation disorders
  • Severe hypertension

Side Effects

  • Elevated serum transaminase levels
  • Allergic reactions
  • Pain at injection site
  • Epidural or spinal hematomas
  • Thrombocytopenia

Pregnancy & Lactation

  • Pregnancy Category B
  • Adverse effects in animal-reproduction studies
  • Precautions during pregnancy and lactation

Precautions & Warnings

  • Patient with increased risk of bleeding complications
  • Increased risk of spinal or epidural hematomas
  • Hepatic and renal impairment
  • Precautions during pregnancy and lactation

Overdose Effects

  • Haemorrhagic complications
  • Management with protamine sulfate

Therapeutic Class

  • Parenteral anticoagulants

Storage Conditions

  • Store between 20-25°C

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