Cardinex 4000 Anti-Xa IU/0.4 ml (SC Injection)

0.4 ml pre-filled syringe: ৳ 400.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Drug international ltd
Also available as
Cardinex 6000 anti xa injection Cardinex 8000 anti xa injection

Title

  • Cardinex

Categories

  • Medicine
  • Anticoagulant

Description

  • Enoxaparin Sodium BP
  • Low molecular weight heparin
  • Anti-Xa activity
  • Pre-filled syringe
  • Subcutaneous injection
  • Pharmacological action
  • Dosage instructions
  • Injection site preparation
  • Interaction with other medications
  • Contraindications
  • Side effects
  • Pregnancy and lactation
  • Storage conditions

Dosage

  • 0.2 ml pre-filled syringe contains 20 mg Enoxaparin Sodium
  • 0.4 ml pre-filled syringe contains 40 mg Enoxaparin Sodium
  • 0.6 ml pre-filled syringe contains 60 mg Enoxaparin Sodium
  • 0.8 ml pre-filled syringe contains 80 mg Enoxaparin Sodium

Indications

  • Deep vein thrombosis treatment
  • Unstable angina and non-Q-wave myocardial infarction treatment
  • Prevention of thrombus formation during hemodialysis
  • Prophylaxis of venous thromboembolic disease

Pharmacology

  • High anti-Xa activity
  • Low anti-lla activity
  • No impact on bleeding time
  • Metabolized in the liver

Composition

  • Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa UI
  • Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa UI

Administration

  • Subcutaneous injection
  • Injection site preparation and selection
  • Dose selection and adjustment based on body weight
  • Disposal of used syringes

Interaction

  • Discontinue agents affecting hemostasis prior to therapy
  • Careful clinical and laboratory monitoring

Contraindications

  • Hypersensitivity to Enoxaparin Sodium or heparin
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain at injection sites
  • Skin rash at injection sites
  • Neuraxial hematomas with spinal anesthesia

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of crossing placental barrier
  • Use during pregnancy only if clearly needed
  • Unknown excretion in human milk

Precautions & Warnings

  • Deep subcutaneous injection
  • Do not administer by intramuscular route
  • Use with caution in conditions with increased potential for bleeding
  • Platelet count monitoring before and during treatment

Use in Special Populations

  • No dosage adjustment in elderly patients
  • Observation in renal impairment patients
  • Caution in hepatically impaired patients

Overdose Effects

  • Hemorrhagic complications
  • Neutralization with protamine sulfate

Therapeutic Class

  • Parenteral anticoagulants

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Storage below 25°C
  • Keep out of reach of children

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