Resitone 20 mg+50 mg (Tablet)
Unit Price: ৳ 6.02 (3 x 10: ৳ 180.60)
Strip Price: ৳ 60.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Furosemide spironolactone |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Chronic congestive heart failure
- Hepatic cirrhosis
- Fluid retention (edema)
- Hyperaldosteronism
- Resistant edema
Pharmacology
- Complementary mechanisms of action
- Additive diuretic effects
- Inhibition of Na+/K+/2Cl- co-transporter
- Blocks reabsorption of sodium, potassium, chloride ions
- Increased urine sodium excretion
- Reduced potassium loss
Dosage & Administration
- Furosemide 20mg and spironolactone 50mg tablets
- Furosemide 40mg and spironolactone 50mg tablets
- Dosage adjustment based on patient's response
- Use not suitable for children
- Elderly excretion considerations
Interaction
- Increased risk of hyperkalemia with ACE inhibitors or potassium salts
- Elevated levels of cardiac glycosides
- Potential digitalis toxicity
- Potential hypokalemia with corticosteroids
- Possible reduction in diuretic effects with NSAIDs
Contraindications
- Anuria
- Acute renal insufficiency
- Severe impairment of renal function
- Hyperkalaemia
- Addison's disease
- Hypersensitivity to components
Side Effects
- Headache
- Drowsiness
- Gastrointestinal distress
- Ataxia
- Mental confusion
- Skin rashes
- Gynaecomastia
- Endocrine disorders
- Hyponatremia
- Hyperkalemia
- Dehydration
- Reduction in blood volume
- Cardiac arrhythmias
Pregnancy & Lactation
- Placental barrier crossing
- Fetal abnormalities
- Metabolites in breast milk
- Considerations for breastfeeding
Precautions & Warnings
- Caution in patients liable to electrolyte deficiency
- Use with caution in diabetes, enlarged prostate, hypotension, hypovolemia
Therapeutic Class
- Potassium-sparing diuretics
- Aldosterone antagonists
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children