Resitone 40 mg+50 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
Category | Details |
---|---|
Generic | Furosemide spironolactone |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Essential hypertension
- Chronic congestive heart failure
- Hepatic cirrhosis
- Swelling due to excess fluid retention
- Hyperaldosteronism
- Resistant edema associated with secondary hyperaldosteronism
Pharmacology
- Potassium sparing diuretic
- Loop diuretic
- Complementary mechanisms
- Additive diuretic effects
- Sodium reabsorption inhibition
- Potassium loss
- Aldosterone antagonism
- Diuretic synergy
Dosage & Administration
- Furosemide 20 and spironolactone 50 mg
- Furosemide 40 and spironolactone 50 mg
- Use in children not suitable
- Elderly excretion
Interaction
- Increased risk of hyperkalemia
- Cardiac glycoside levels increase
- Potential digitalis toxicity
- Hypokalemia with corticosteroids
- Reduced diuretic effects with NSAIDs
- Ototoxicity increase with antibiotics
Contraindications
- Anuria
- Acute renal insufficiency
- Impairment of renal function
- Hyperkalaemia
- Addison's disease
- Hypersensitivity to Spironolactone or Furosemide
Side Effects
- Headache
- Drowsiness
- Gastrointestinal distress
- Ataxia
- Mental confusion
- Skin rashes
- Gynaecomastia
- Endocrine disorders
- Increase in blood-urea-nitrogen concentrations
- Mild acidosis
- Hyponatremia
- Hyperkalemia
- Dehydration
- Reduction in blood volume
- Cardiac arrhythmias
Pregnancy & Lactation
- Fetal abnormalities with Furosemide
- Pregnant women benefit vs. hazards assessment
- Metabolites in breast milk
- Alternative infant feeding method
- Discontinue breastfeeding if essential
Precautions & Warnings
- Caution in patients liable to electrolyte deficiency
- Caution in diabetes
- Caution in enlarged prostate
- Caution in hypotension
- Caution in hypovolemia
Therapeutic Class
- Potassium-sparing diuretics
- Aldosterone antagonists
Storage Conditions
- Keep below 30°C
- Keep away from light & moisture
- Keep out of the reach of children