Resitone 40 mg+50 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Indications

  • Essential hypertension
  • Chronic congestive heart failure
  • Hepatic cirrhosis
  • Swelling due to excess fluid retention
  • Hyperaldosteronism
  • Resistant edema associated with secondary hyperaldosteronism

Pharmacology

  • Potassium sparing diuretic
  • Loop diuretic
  • Complementary mechanisms
  • Additive diuretic effects
  • Sodium reabsorption inhibition
  • Potassium loss
  • Aldosterone antagonism
  • Diuretic synergy

Dosage & Administration

  • Furosemide 20 and spironolactone 50 mg
  • Furosemide 40 and spironolactone 50 mg
  • Use in children not suitable
  • Elderly excretion

Interaction

  • Increased risk of hyperkalemia
  • Cardiac glycoside levels increase
  • Potential digitalis toxicity
  • Hypokalemia with corticosteroids
  • Reduced diuretic effects with NSAIDs
  • Ototoxicity increase with antibiotics

Contraindications

  • Anuria
  • Acute renal insufficiency
  • Impairment of renal function
  • Hyperkalaemia
  • Addison's disease
  • Hypersensitivity to Spironolactone or Furosemide

Side Effects

  • Headache
  • Drowsiness
  • Gastrointestinal distress
  • Ataxia
  • Mental confusion
  • Skin rashes
  • Gynaecomastia
  • Endocrine disorders
  • Increase in blood-urea-nitrogen concentrations
  • Mild acidosis
  • Hyponatremia
  • Hyperkalemia
  • Dehydration
  • Reduction in blood volume
  • Cardiac arrhythmias

Pregnancy & Lactation

  • Fetal abnormalities with Furosemide
  • Pregnant women benefit vs. hazards assessment
  • Metabolites in breast milk
  • Alternative infant feeding method
  • Discontinue breastfeeding if essential

Precautions & Warnings

  • Caution in patients liable to electrolyte deficiency
  • Caution in diabetes
  • Caution in enlarged prostate
  • Caution in hypotension
  • Caution in hypovolemia

Therapeutic Class

  • Potassium-sparing diuretics
  • Aldosterone antagonists

Storage Conditions

  • Keep below 30°C
  • Keep away from light & moisture
  • Keep out of the reach of children

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