Zerotil 1.5 gm/vial (IV Injection)
1.5 gm vial: ৳ 275.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by various bacteria
- Acute bacterial maxillary sinusitis caused by certain bacteria
- Lower respiratory tract infections including pneumoniae caused by various bacteria
- Acute bacterial exacerbation of chronic bronchitis
- Secondary bacterial infections of Acute bronchitis
- Skin and skin-structure infections caused by specific bacteria
- Urinary tract infections caused by specific bacteria
- Bone and Joint Infections caused by specific bacteria
- Gonorrhoea caused by specific strains of Neisseria gonorrhoeae
- Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
Pharmacology
- Broad-spectrum bactericidal activity
- Effective against β-lactamase producing strains
- Good stability to bacterial β-lactamase
Dosage
- Tablet or Suspension for Adolescents and adults (13 years and older)
- Pharyngitis/tonsillitis dosage
- Acute bacterial maxillary sinusitis dosage
- Acute bacterial exacerbation of chronic bronchitis dosage
- Secondary bacterial infections of acute bronchitis dosage
- Uncomplicated skin and skin structure infections dosage
- Uncomplicated urinary tract infections dosage
- Uncomplicated Gonorrhoea dosage
- Community acquired pneumonia dosage
- MDR Typhoid Fever dosage
- Early Lyme disease dosage
- Dosage for Paediatric Patients (3 months to 12 years)
- Dosage for Parenteral administration in Adults
- Dosage for Children (above 3 months of age)
- Dosage for Neonate
- Dosage for Surgical prophylaxis
- Dosage for Pneumonia
- Dosage for Acute exacerbations of chronic bronchitis
- Dosage for In Gonorrhoea
- Dosage for Meningitis
- Dosage for bone and joint infections
Administration
- Use of freshly reconstituted solution recommended
- Maintains potency for at least 24 hours at room temperature
- Maintains potency for 48 hours at 5° C
Interaction
- No potentially hazardous interactions reported
Contraindications
- Contraindicated in patients with known allergy to Cephalosporins
Side Effects
- Adverse effects have occurred infrequently
- Effects reported include rashes and gastrointestinal disturbances
- Prolonged use may result in the overgrowth of non susceptible organisms e.g. Candida
Pregnancy & Lactation
- US FDA pregnancy category of Cefuroxime is B
- No adequate and well-controlled studies in pregnant women
- Cefuroxime excreted in human milk
Precautions & Warnings
- Use with care in patients receiving concurrent treatment with potent diuretics and with history of colitis
- Cephalosporin antibiotics may be given safely to patients who are hypersensitive to penicillin
- Cross reactions have been reported
- Likely not a problem at the recommended dose levels
Therapeutic Class
- Second generation Cephalosporins
Reconstitution
- Specific reconstitution instructions for intramuscular and intravenous injection
Storage Conditions
- Store in a cool, dry place (below 30° C)
- Away from light and moisture
- Keep out of the reach of children