Helben DS 400 mg (Chewable Tablet)

Unit Price: ৳ 4.00 (50's pack: ৳ 200.00)

Medicine Details

Category Details
Generic Albendazole
Company Modern pharmaceuticals ltd

Indications

  • Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid

Description

  • Benzimidazole anthelmintic
  • Active against most nematodes and some cestodes
  • Used in the treatment of intestinal nematode infections
  • Exhibits vermicidal, ovicidal, and larvicidal activity
  • Inhibitory effect on tubulin polymerization

Pharmacology

  • Broad spectrum anthelmintic
  • Exhibits vermicidal, ovicidal, and larvicidal activities
  • Blocks glucose uptake in susceptible helminths
  • Exerts anthelmintic effect by immobilizing parasites
  • Extensively metabolized, probably in the liver
  • Poorly absorbed from the gastrointestinal tract

Dosage & Administration

  • Recommended dose for adults and children over 2 years is 400 mg as a single dose for certain infections
  • Recommended dose for children of 1-2 years is 200 mg as a single dose
  • Not recommended for children under 1 year
  • In Hydatid disease, recommended doses vary based on patient weight and kind of echinococcosis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Not recommended for neonates
  • Possible reduction of dose for children weighing less than 10 kg
  • Avoid use in pregnant women
  • No alteration of dose required for renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

  • Pregnancy category is C
  • Avoid use in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before and during treatment
  • Exclusion of pregnancy before treatment
  • Constant medical supervision during treatment of Echinococcosis

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in a dry place
  • Away from light and heat
  • Keep out of the reach of children

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