Dexifen 400 mg (Tablet)

Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Relief of sign and symptoms of osteoarthritis
  • Rheumatoidal disorders treatment
  • Painful menstruation treatment
  • Headache and fever relief
  • Symptomatic treatment of mild to moderate pain
  • Adjuvant with common cold and influenza
  • Muscle pain relief

Pharmacology

  • Pharmacologically active enantiomer of racemic ibuprofen
  • Non-steroidal anti-inflammatory drug
  • Analgesic action
  • Inhibition of prostaglandin synthesis
  • Absorption from small intestine
  • Metabolic transformation in the liver
  • Excretion through kidneys and bile
  • Plasma protein binding
  • Maximum plasma levels and time to reach them
  • Effect of administration with a meal

Dosage & Administration

  • Dosage adjustment to seriousness of syndrome and patient's complaints
  • Recommended dosage of Dexibuprofen per day
  • Temporary dosage raise for acute disorders
  • Maximum daily dose
  • Dosage for dysmenorrhea

Interaction

  • Similar drug interactions to racemic mixture of ibuprofen
  • Simultaneous use interactions with various drugs

Contraindications

  • Previous history of hypersensitivity to Dexibuprofen or NSAID
  • Contraindicated in asthma, bronchospasm, acute rhinitis, urticaria, or edema
  • Contraindicated in active or suspected hemorrhage, Crohn's disease, ulcerative colitis, serious heart diseases, kidney function impairment, and liver function impairment

Side Effects

  • Common side-effects similar to racemic ibuprofen
  • Dyspepsia, diarrhea, fatigue, headache, nausea, vomiting, abdominal pain
  • Hypersensitivity reactions, bleeding, ulcer

Pregnancy & Lactation

  • Avoid use during pregnancy
  • Effects on fetal cardiovascular system
  • Caution in nursing mothers

Precautions & Warnings

  • Caution in patients with bronchial asthma or chronic pulmonary diseases
  • Use in patients with hepatic, renal, or cardiac insufficiency and hypertension
  • Consultation with a doctor for patients with systemic lupus or other autoimmunological disease
  • Caution in hemorrhagic conditions and allergic reactions

Use in Special Populations

  • Caution in patients with hepatic, renal, or cardiac insufficiency
  • Use in children and elderly
  • Dosage for children aged 6 years and over
  • Lowest effective dose for elderly
  • Renal and hepatic impairment dose adjustments

Overdose Effects

  • Low acute toxicities
  • Symptoms of toxicity at specific doses
  • Mild to serious symptoms
  • Symptomatic treatment
  • Activated charcoal administration
  • Induced vomiting and timing
  • Dialysis and hemodialysis value

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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