Staxiclav 250 mg+62.5 mg (Tablet)

Unit Price: ৳ 30.00 (3 x 4: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Delta pharma ltd
Also available as
Staxiclav 500 mg tablet

Title

  • Staxiclav 250 mg Tablet

Categories

  • Antibiotics
  • Prescription Medication
  • Infectious Disease Treatment

Description

  • Staxiclav 250 mg Tablet is indicated for the treatment of infections caused by sensitive bacteria. It is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains.
  • It is used to treat various conditions such as pharyngitis, tonsillitis, sinusitis, bronchitis, skin and skin-structure infections, urinary tract infections, gonorrhea, pneumonia, typhoid fever, and more.
  • Cefuroxime, the active ingredient, inhibits bacterial cell wall synthesis by interfering with the transpeptidation process. Clavulanic acid, another component, is a beta lactamase inhibitor that protects cefuroxime from degradation by beta lactamase enzymes.

DosageAndAdministration

  • 250 mg b.i.d. for 5-10 days for pharyngitis/tonsillitis in adolescents and adults
  • Adolescents and adults may take 250-500 mg b.i.d. for 5-10 days for uncomplicated skin and skin structure infections
  • 250 mg b.i.d. for 7-10 days for uncomplicated urinary tract infections in adolescents and adults
  • 20 mg/kg/day b.i.d for 5-10 days for pharyngitis/tonsillitis in pediatric patients
  • 30 mg/kg/day b.i.d for 10 days for acute otitis media in pediatric patients

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%.

Contraindications

  • Cefuroxime-Clavulanic Acid is contraindicated in patients with known allergy to cephalosporin & in patients with Pseudomembranous Colitis.

SideEffects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash
  • Serum sickness like urticaria

PregnancyAndLactation

  • Antibiotics should be avoided in the first trimester if possible. However, Cefuroxime-Clavulanic Acid can be safely used in later pregnancy to treat urinary and other infections.
  • Cefuroxime-Clavulanic Acid is excreted into the breast milk in small quantities. Sensitizing the infant should be kept in mind.

PrecautionsAndWarnings

  • Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis.

TherapeuticClass

  • Second generation Cephalosporins

StorageConditions

  • Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis (beta-lactamase producing strains) or Streptococcus pyogenes
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae (non beta-lactamase producing strains)
  • Lower respiratory tract infections including pneumoniae, caused by Streptococcus pneumoniae, Haemophilus influenzae (including beta lactamase-producing strains), Klebsiella spp., Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains), Streptococcus pyogenes, E. coli
  • Acute bacterial exacerbation of chronic bronchitis and secondary bacterial infections of Acute bronchitis caused by Streptococcus pneumoniae, Haemophilus influenzae (beta-lactamase negative strains) or Haemophilus parainfluenzae (beta-lactamase negative strains)
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus (including beta-lactamase producing strains) or Streptococcus pyogenes
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus (penicillinase- and non-penicillinase-producing strains)
  • Uncomplicated Gonorrhoea caused by penicillinase-producing and non-penicillinase producing strains of Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (including ampicillin-resistant strains) & Klebsiella spp
  • Meningitis caused by Streptococcus pneumoniae, Haemophilus influenzae (including ampicillin-resistant strains), Neisseria meningitidis & Staphylococcus aureus (penicillinase and non-penicillinase producing strains)
  • Switch therapy (Injectable to oral)

CommonlyAskedQuestions

  • Staxiclav 250 mg Tablet starts working within 2-3 hours after taking it.
  • The effect of Staxiclav 250 mg Tablet lasts for an average duration of 4-8 hours.

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