Cosmozole 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 6.50 (10 x 10: ৳ 650.00)
Strip Price: ৳ 65.00

Medicine Details

Category Details
Generic Esomeprazole
Company Cosmo pharma laboratories ltd
Also available as
Cosmozole 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Relief from other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related dyspepsia
  • Treatment of duodenal and gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Single optical isomer of proton pump inhibitor (S-isomer of omeprazole)
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Absorption peak plasma levels at approximately 1.5 hours
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Different dosages for different indications
  • Oral dosages for pediatric patients based on body weight

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension should be mixed with water and consumed within 30 minutes
  • IV injection should be administered over a period of at least 3 minutes

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion may interfere with drug absorption

Contraindications

  • Hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if esomeprazole use is essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Instructions for patients on capsule administration and swallowing difficulties

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed between elderly and younger individuals

Overdose Effects

  • Signs of acute toxicity
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular formula: C17H19N3O3S

Common Questions about Cosmozole 20 mg Capsule

  • Information about the medication
  • Uses of the capsule
  • Side effects and their similarity between long-term and short-term use
  • Safety during pregnancy and breastfeeding
  • Onset of action and quick tips for usage

Related Brands