Etoshine 60 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Sun pharmaceutical bangladesh ltd |
| Also available as |
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Pain relief after dental surgery
Pharmacology
- Potent COX-2 inhibitor
- Decreased potential for gastrointestinal toxicity
- Decreased platelet aggregation effects
Dosage & Administration
- 30 mg once daily for osteoarthritis
- 60 mg once daily if insufficient relief from symptoms
- 90 mg once daily for rheumatoid arthritis and ankylosing spondylitis
- 120 mg once daily for acute gouty arthritis
- Maximum of 3 days for postoperative dental surgery pain
Interactions
- Increase in prothrombin time with oral anticoagulants
- Reduction in diuretics and antihypertensive drugs' effects with NSAIDs
- Concomitant use with low-dose acetylsalicylic acid for cardiovascular prophylaxis
- Potential increase in nephrotoxic effect with ciclosporin or tacrolimus
- Decreased lithium renal excretion with NSAIDs
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or gastrointestinal bleeding
- History of allergic-type reactions to NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Uncontrolled hypertension
- Established ischaemic heart disease, peripheral arterial disease, or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excretion in rat milk, not known in human milk
- Not recommended for breastfeeding women
Precautions & Warnings
- Caution in patients at risk of gastrointestinal complications with NSAIDs
- Careful consideration in patients with significant cardiovascular risk factors
- Monitoring of renal function due to potential impairment
- Caution in patients with history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring for liver dysfunction or abnormal liver function tests
- Discontinuation at first appearance of hypersensitivity signs
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- No significant toxicity observed with recommended doses
- Employ usual supportive measures if overdose occurs
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Below 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure Image URL
Common Questions
- Onset of action within 1-2 hours
- Duration of effect lasts for an average of 20-24 hours
- Not recommended for pregnant or breastfeeding women
- No habit forming tendencies reported
- Unsafe to consume with alcohol
- May affect patient's alertness, thus avoid driving
- Caution needed in patients with kidney or liver disease
- Regular blood pressure monitoring during treatment