Lonazep MD 0.5 mg (Dispersible Tablet)

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Clonazepam
Company Sun pharmaceutical bangladesh ltd
Also available as
Lonazep 05 mg tablet Lonazep 2 mg tablet Lonazep md 1 mg tablet Lonazep md 2 mg tablet

Title

  • Lonazep MD 0.5 mg Tablet

Categories

  • Anti-epileptic Drugs
  • Benzodiazepine Hypnotics

Description

  • Indicated for the treatment of panic disorder, with or without agoraphobia
  • Exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects
  • Dosage must be individualized for each patient depending upon response

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Adjunct in the treatment of Lennox-Gastaut Syndrome
  • Treatment of akinetic and myoclonic seizures
  • May be indicated in patients with absence seizures who have failed to respond to succinimides

Pharmacology

  • Enhances GABAergic neurotransmission at inhibitory synapses
  • Suppresses many types of paroxysmal activity including spike and wave discharge in absences seizures

Dosage & Administration

  • Initial dose should not exceed 1.5 mg/day for adults with seizure disorders
  • Initial dose for adults with panic disorder is 0.25 mg

Interaction

  • Does not appear to alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital

Contraindications

  • History of hypersensitivity to benzodiazepines
  • Patients with clinical or biochemical evidence of significant liver disease
  • Contraindicated in acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness in approximately 50% of patients
  • Ataxia in approximately 30% of patients

Pregnancy & Lactation

  • Should only be administered to pregnant women if the potential benefits outweigh the risk to the fetus
  • Breastfeeding should be discontinued if there is a compelling indication for Clonazepam

Precautions & Warnings

  • May increase the incidence or precipitate the onset of generalized tonic-clonic seizures in certain patients
  • The concomitant use of valproic acid and Lonazep MD may produce absence status

Use in Special Populations

  • May cause increased production of saliva and bronchial secretion in infants and small children
  • Benzodiazepine pharmacologic effects appear to be greater in elderly patients

Overdose Effects

  • Symptoms may include drowsiness, ataxia, and dysarthria
  • Monitor the patient's vital signs and institute supportive measures as indicated

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • The contents of the vial must be diluted with 1 ml of water for injection prior to administration
  • IV injection should be administered slowly with continuous monitoring of EEG, respiration, and blood pressure
  • Lonazep MD can be diluted for infusion in a ratio of 1 vial (1 mg) to at least 85 ml diluting media

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C15H10ClN3O3

Commonly Asked Questions

  • Lonazep MD 0.5 mg DT is not used as a sleeping pill
  • You need to take Lonazep MD 0.5 mg DT as long as the doctor has advised you
  • The common symptoms after stopping Lonazep MD 0.5 mg DT are difficulty in sleeping and changes in mood
  • Monitor for early symptoms of suicidal thoughts and actions
  • In some cases, Lonazep MD 0.5 mg DT might cause weight gain and weight loss
  • Lonazep MD 0.5 mg DT does not affect memory
  • Overdose can cause sleepiness, change in speech, confusion, and abnormalities in eye movement
  • The combination of Lonazep MD 0.5 mg DT and zolpidem should be avoided
  • The combination of Lonazep MD 0.5 mg DT and quetiapine may increase side effects

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