Lonazep MD 2 mg (Dispersible Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Sun pharmaceutical bangladesh ltd |
| Also available as |
Indications
- Treatment of panic disorder
- Treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Adjunct in the treatment of the Lennox-Gastaut Syndrome
- Treatment of absence seizures (petit mal)
- Treatment failure indication for patients with absence seizures
- Long-term use caution
- Periodic reevaluation of long-term usefulness
Pharmacology
- Anticonvulsive effects
- Sedative effects
- Muscle relaxing effects
- Anxiolytic effects
- Enhancement of GABAergic neurotransmission
- Positive allosteric modulation of GABA receptor
- Effect on serotonin
- Suppression of paroxysmal activity
- Beneficial effects in generalized and focal epilepsies
Dosage & Administration
- Initial dose for adults with seizure disorders
- Initial dose for adults with panic disorder
- Dosage increment after 3 days
- Initial dose for pediatric patients
- Administration via oral route
- Administration via injection
- Dosage limits for adults
- Dosage limits for pediatric patients
Interaction
- Limited alteration of phenytoin, carbamazepine, phenobarbital pharmacokinetics
- Effects on the metabolism of other drugs
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Not for patients with acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Confusion
- Depression
- Amnesia
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential to produce congenital malformations
- Epidemiological evidence of teratogenicity
- Consideration for administration during pregnancy
- Potential effects in the last trimester of pregnancy
- Influence on the newborn
- Passage into maternal milk
- Recommendation to discontinue breastfeeding if administered
Precautions & Warnings
- Increased incidence of generalized tonic-clonic seizures
- Coexistence with other seizure disorders
- Concomitant use of valproic acid
- Potential effects in special populations
- Effects on elderly patients
- Effects in patients with renal impairment
- Effects in patients with hepatic impairment
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in elderly patients
- Unaffected pharmacokinetics in renal impairment
- Significant difference in plasma protein binding in cirrhotic patients
Overdose Effects
- Common symptoms of overdose
- Rare life-threatening effects
- Increased frequency of seizures
- Respiratory depressant effects
- Interactions with other central nervous system depressants
- Monitoring and supportive measures in overdose treatment
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Requirements for slow intravenous injection
- Requirements for intravenous infusion
- Requirements for intramuscular injection
Storage Conditions
- Recommendation for dry place away from light and heat
- Recommendation to keep out of the reach of children
Chemical Structure
- Molecular formula
- Chemical structure image
Common Questions
- Medication use as a sleeping pill
- Duration of medication use
- Withdrawal symptoms after stopping medication
- Early symptoms of suicidal thoughts and actions
- Effect on weight
- Effect on memory
- Harmful effects of exceeding recommended doses
- Potential interactions with other medications
- Quick tips for medication use