Sizodon MD 4 mg (Dispersible Tablet)

Unit Price: ৳ 9.50 (5 x 10: ৳ 475.00)
Strip Price: ৳ 95.00

Medicine Details

Indications

  • Treatment of acute and chronic psychoses
  • Treatment of mania
  • Treatment of schizophrenia

Pharmacology

  • Selective monoaminergic antagonist
  • High affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors
  • Binds to alpha1 adrenergic receptors
  • Binds with lower affinity to H1 histamine and alpha2 adrenergic receptors
  • Potent D2 antagonist

Dosage & Administration

  • Initial dose of 2 mg in 1-2 divided doses on 1st day
  • Usual dose range of 4-6 mg daily
  • Maximum dose of 16 mg daily
  • Dosing adjustments for elderly or patients with hepatic or renal impairment
  • Different dosage recommendations for psychoses, mania, and schizophrenia

Interaction

  • Antagonizes the effects of levodopa and dopamine agonists
  • Reduces plasma clearance when administered with Carbamazepine
  • May decrease clearance when administered with Clozapine
  • Enhances the effects of certain antihypertensives

Contraindications

  • Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Urine incontinence
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neurtropenia
  • Thrombocytopenia

Pregnancy & Lactation

  • No established safety for use during human pregnancy
  • Excreted in human breast milk

Precautions & Warnings

  • Precaution for preexisting cardiovascular diseases
  • Discontinue use if signs and symptoms of tardive dyskinesia occur
  • Special precaution for renal and hepatic impairment, elderly, epilepsy, and Parkinson's disease

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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