Sompraz 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sun pharmaceutical bangladesh ltd
Also available as
Sompraz 20 mg tablet Sompraz 40 mg tablet Sompraz 20 mg capsule

Intended Use

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal & Gastric ulcers

Pharmacological Action

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Single optical isomer providing better acid control
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Metabolized in the liver by the cytochrome P450 enzyme system

Dosage Forms

  • Tablet
  • Capsule
  • Oral Suspension
  • IV Injection
  • IV Infusion

Dosage Instructions

  • 20 mg or 40 mg Once Daily for healing of erosive esophagitis
  • 20 mg Once Daily for maintenance of healing of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for Duodenal ulcer
  • 20-40 mg once daily for 4-8 weeks for Gastric ulcer
  • Specific dosages for IV administration based on patient's weight and condition

Administration Instructions

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with water and consumed within 30 minutes
  • IV Injection should be administered intravenously over a period of at least 3 minutes

Interactions

  • Metabolized by CYP2C19 and CYP3A4
  • No clinically significant interactions with specific drugs
  • Potential interference with absorption of certain drugs due to inhibition of gastric acid secretion

Contraindications

  • Known hypersensitivity to any of the formulation

Adverse Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No excretion data in breast milk
  • Discontinuation of breastfeeding if essential use of esomeprazole is considered

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall safety and efficacy differences in geriatric use
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • Unaltered Pharmacokinetics in renal impairment

Overdose Effects

  • Signs of acute toxicity in rats
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image Available

Commonly Asked Questions

  • Intended use of Sompraz 40 mg Capsule
  • Side effects and their nature
  • Pregnancy and breastfeeding considerations
  • Onset of action and quick tips for usage

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