Etoshine 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Sun pharmaceutical bangladesh ltd |
| Also available as |
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Dental surgery pain
Pharmacology
- Potent
- Orally active
- Cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 without inhibition of COX-1
- Decrease in clinical signs and symptoms
- Decreased potential for GI toxicity
- Effect on platelet aggregation
- Dose-dependent inhibition of COX-2
Dosage & Administration
- Recommended dose for osteoarthritis: 30mg once daily
- Recommended dose for rheumatoid arthritis: 90mg once daily
- Recommended dose for ankylosing spondylitis: 90mg once daily
- Recommended dose for acute gouty arthritis: 120mg once daily
- Recommended dose for postoperative dental surgery pain: 90mg once daily
- Shortest duration and lowest effective daily dose should be used
- Re-evaluation of patient's need for symptomatic relief and response to therapy
Interaction
- Increase in prothrombin time with oral anticoagulants
- Reduction in the effect of diuretics and other antihypertensive drugs with NSAIDs
- Concomitant use with low-dose acetylsalicylic acid for cardiovascular prophylaxis
- Potential increase in the nephrotoxic effect of ciclosporin or tacrolimus with coadministration
- Decrease in lithium renal excretion and increase in lithium plasma levels with NSAIDs
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- Experienced hypersensitivity reactions to acetylsalicylic acid or NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance < 30ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Uncontrolled hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excreted in the milk of lactating rats
- Not recommended for breastfeeding women
Precautions & Warnings
- Caution in patients at risk of developing GI complication with NSAIDs
- Careful consideration in patients with significant risk factors for cardiovascular events
- Potential reduction in prostaglandin formation and renal blood flow
- Exercise caution in patients with history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of renal and hepatic function
- Discontinuation at first sign of skin rash, mucosal lesions, or hypersensitivity
- Potential masking of fever and other signs of inflammation
- Caution with co-administration with warfarin or other oral anticoagulants
Overdose Effects
- No significant toxicity observed with single or multiple doses up to specified limits
- Employment of usual supportive measures in case of overdose
Therapeutic Class
Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Below 30°C, protect from light and moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Etoshine 90 mg Tablet
- Selective COX-2 inhibitor
- Symptomatic relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
- Duration of effect: 20-24 hours
- Onset of action within 1-2 hours
- Not recommended for pregnant or breastfeeding women
- Not habit forming
- Unsafe to consume with alcohol
- May affect alertness, unsafe for driving
- Caution in patients with kidney or liver disease