Etoshine 120 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Pain associated with dental surgery

Pharmacology

  • Potent orally active COX-2 specific inhibitor
  • Inhibition of prostaglandin-mediated pain, inflammation, and fever
  • Selective inhibition of COX-2
  • Decreased potential for GI toxicity

Dosage and administration

  • Recommended doses for different conditions
  • Potential need for increased dose for insufficient relief

Interaction

  • Interaction with oral anticoagulants
  • Reduction of effect of diuretics and antihypertensive drugs
  • Concomitant use with low-dose acetylsalicylic acid
  • Potential interaction with ciclosporin, tacrolimus, and lithium

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or GI bleeding
  • History of allergic-type reactions to NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance < 30 ml/min

Side effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Dry mouth
  • Taste disturbance
  • Chest pain
  • Cough
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy and lactation

  • Not recommended for women attempting to conceive
  • Excretion in human milk and lactating rats

Precautions and warnings

  • Caution with patients at risk of GI complications
  • Careful consideration for patients with cardiovascular risk factors
  • Potential reduction in prostaglandin formation and renal blood flow
  • Caution with history of cardiac failure, edema, or liver dysfunction
  • Monitoring of renal and hepatic function
  • Discontinuation at first sign of hypersensitivity

Overdose effects

  • Lack of significant toxicity in specified doses
  • Employment of usual supportive measures in case of overdose

Therapeutic class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage conditions

Store at temperature below 30°C, protect from light and moisture, keep out of reach of children

Chemical structure

  • Molecular formula: C18H15ClN2O2S
  • Chemical structure image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Commonly asked questions

  • What is Etoshine 120mg Tablet: Selective COX-2 inhibitor for pain, inflammation, and fever relief
  • Uses of Etoshine 120mg Tablet: Relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
  • Duration of effect of Etoshine 120mg Tablet: 20-24 hours
  • Onset of action of Etoshine 120mg Tablet: 1-2 hours, faster on empty stomach
  • Pregnancy warnings of Etoshine 120mg Tablet: Not recommended, consult doctor
  • Habit forming of Etoshine 120mg Tablet: No habit forming tendencies reported
  • Breast feeding warnings of Etoshine 120mg Tablet: Not recommended, consult doctor
  • Safety with alcohol: Unsafe to consume with alcohol
  • Safety to drive while on this medicine: May affect patient's alertness, avoid driving
  • Effect on kidney function: Caution and dose adjustment in kidney disease
  • Effect on liver function: Caution and dose adjustment in liver disease
  • Quick tips:
    • Helps relieve pain and inflammation
    • May cause fewer stomach problems compared to other NSAIDs
    • May cause dizziness and fatigue, avoid activities requiring concentration
    • Avoid alcohol consumption
    • Regular blood pressure monitoring
    • Inform doctor about medical history
    • Regular blood tests during long-term treatment
    • Not recommended for pregnant, planning to conceive, or breastfeeding

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