Dexkof Plus (20 mg+10 mg+2.5 mg)/5 ml (Syrup)
100 ml bottle: ৳ 100.00
Medicine Details
Category | Details |
---|---|
Generic | Dextromethorphan phenylephrine triprolidine |
Company | Sharif pharmaceuticals ltd |
Indications
- Temporarily relieves symptoms of common cold
- Temporarily relieves symptoms of hay fever
- Temporarily relieves symptoms of other upper respiratory allergies
- Relieves cough due to throat irritation
- Relieves cough due to bronchial irritation
- Relieves runny nose
- Relieves sneezing
- Relieves itching of the nose or throat
- Relieves itchy, watery eyes
- Relieves nasal congestion
- Reduces swelling of nasal passages
Pharmacology
- Mixture of antitussive, decongestant, and antihistamine agent
- Contains dextromethorphan as a non-narcotic antitussive agent
- Contains phenylephrine as a decongestant
- Contains triprolidine as a competitive histamine H1-receptor antagonist
Dosage
- Recommended dosage for adults and children 12 years of age and older: 1 teaspoonful (5 ml) every 4 hours
- Recommended dosage for children 6 to under 12 years of age: ½ teaspoonful (2.5 ml) every 4 hours
- Recommended dosage for children 2 to 6 years: To be used with caution and as advised by the physician
- Not to be used in children below 2 years old
Administration
- Can be taken with or without food
- Liquid doses should be measured carefully
- Use the measuring device that comes with this medicine
Interaction
- May interact with certain MAO inhibitors
- Caution should be exercised when taking with antihistamines, antispasmodics, beta blockers, drugs for Parkinson’s disease, guanethidine, inhaled anesthetics, methyldopa, reserpine, scopolamine, tricyclic antidepressants, anti-seizure drugs, medicine for sleep or anxiety, muscle relaxants, narcotic pain relievers, or psychiatric medicines
Contraindications
- Avoid in patients with liver disease
- Avoid in asthmatic patients
- Contraindicated in patients taking monoamine oxidase inhibitors or within 2 weeks from stopping such treatment
- Contraindicated in patients with known hypersensitivity to phenylephrine hydrochloride or dextromethorphan hydrobromide
- Contraindicated during acute attacks of asthma
- Contraindicated in patients with severe hypertension
- Contraindicated in patients with severe coronary artery disease
Side Effects
- May cause drowsiness
- May cause dottiness
- May cause constipation
- Other side effects may include GIT discomfort, transient hypertension, dry mouth, restlessness, palpitations, allergic reactions, toxic psychosis, and blood dyscrasia
Pregnancy & Lactation
- Avoid use in pregnancy and lactation
Precautions & Warnings
- May cause drowsiness
- Avoid driving or operating machinery if affected
- Avoid alcoholic drinks while on this medication
- Use with caution in patients with epilepsy, prostatic hypertrophy, glaucoma, hepatic disease, hypertension, heart disease, diabetes, hyperthyroidism, patients with stenosing peptic ulcer, pyloro-duodenal obstruction, or bladder neck obstruction
- Consult a physician if symptoms do not improve within one week or are accompanied by high fever
Overdose Effects
- Hospital admission is strongly advised in cases of overdose
- Overdose may produce respiratory depression, paranoid psychosis, delusions, hallucinations, and convulsions
- Treatment should include emptying the stomach by aspiration or gastric lavage
- Nervous stimulation and convulsions should be treated with a sedative such as diazepam intramuscularly
- Severe overdose of phenylephrine hydrochloride may produce hypertension and associated reflex bradycardia
Therapeutic Class
- Combined cough suppressants
Storage Conditions
- Keep out of the reach of children
- Store in a cool and dry place
- Protect from light
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