Biotrex 40 mg/5 ml (Syrup)

30 ml bottle: ৳ 15.00

Medicine Details

Category Details
Generic Levamisole
Company Biopharma limited

Indications

  • Treats gastrointestinal worm infections
  • Effective against roundworm, hookworm, pinworm, whipworm, threadworm

Pharmacology

  • Active ingredient: Levamisole
  • Paralyses susceptible intestinal worms
  • Enhances cellular immune responses in humans

Dosage & Administration

  • Single administration after a light meal
  • Dosage varies based on age: 1-4 years, 5-15 years, 16 years and over
  • Additional dose recommended for severe hookworm infection

Interaction

  • May increase phenytoin toxicity
  • Increases bioavailability of ivermectin
  • Decreases bioavailability of albendazole
  • Alcohol causes disulfiram-like reaction

Contraindications

  • No absolute contraindications to the use of Levamisole

Side Effects

  • Infrequent and mild
  • Transient side effects: nausea, vomiting, abdominal pain, dizziness, headache
  • Encephalopathy-like syndrome reported in some patients

Pregnancy & Lactation

  • Animal studies show no teratogenic effects
  • Benefits should be weighed against potential dangers during pregnancy

Precautions & Warnings

  • No evidence of sedation
  • Mild and transient giddiness as infrequent side effect
  • No precautions for driving or operating machinery
  • Transient fever possible in case of concurrent microfilaraemia

Overdose Effects

  • Counter anticholinesterase activity with atropine
  • Control blood pressure and respiration
  • Avoid sedatives

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Tablets: Store in room temperature and protect from moisture
  • Syrup: Store in room temperature and protect from light

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