Enoma 4000 Anti-Xa IU/0.4 ml (SC Injection)

0.4 ml pre-filled syringe: ৳ 400.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Biopharma limited
Also available as
Enoma 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis, with or without pulmonary embolism
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in the extra-corporal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease in surgical patients
  • Prophylaxis of venous thromboembolic disease in medical patients

Composition

  • Each 0.2 ml pre-filled syringe contains Enoxaparin Sodium BP 20 mg
  • Each 0.4 ml pre-filled syringe contains Enoxaparin Sodium BP 40 mg
  • Each 0.6 ml pre-filled syringe contains Enoxaparin Sodium BP 60 mg
  • Each 0.8 ml pre-filled syringe contains Enoxaparin Sodium BP 80 mg

Pharmacology

Low molecular weight heparin with high anti-Xa activity and low anti-lla or antithrombin activity

Dosage

  • Subcutaneously 100 anti-Xa lU/kg twice daily for 10 days
  • Oral anticoagulant therapy initiation when appropriate
  • Subcutaneously 100 anti-Xa lU/kg twice daily for 2-8 days concurrently with oral aspirin
  • Recommended dose of 100 anti-Xa lU/kg for prevention of thrombus formation during hemodialysis
  • Different doses based on risk for surgical and medical patients

Administration

  • Injection site preparation guidelines
  • Instructions on selecting and adjusting dose
  • Guidelines for injecting and handling used syringes

Interaction

Recommendation to discontinue agents affecting hemostasis prior to therapy

Contraindications

Hypersensitivity to Enoxaparin Sodium, active major bleeding, high risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage (bleeding)
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain and skin reactions at injection sites
  • Cases of neuraxial hematomas with spinal/epidural anesthesia

Pregnancy & Lactation

Pregnancy category B, caution in nursing mothers

Precautions & Warnings

  • Administer by deep subcutaneous or intravascular route
  • Caution in conditions with increased potential for bleeding
  • Recommendation for platelet count measurement

Use in Special Populations

  • No dosage adjustment for elderly patients
  • Observation for signs of bleeding in renal impairment
  • Caution in hepatically impaired patients

Overdose Effects

Accidental overdosage may lead to hemorrhagic complications

Therapeutic Class

Parenteral anti-coagulants

Storage Conditions

Store in a cool and dry place, protect from light and moisture, below 25°C

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