Cloma 1 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Clonazepam
Company Biopharma limited
Also available as

Indications

  • Treatment of panic disorder with or without agoraphobia
  • Treatment of Lennox-Gastaut Syndrome
  • Treatment of epileptic seizures

Pharmacology

  • Anticonvulsive effects
  • Sedative effects
  • Muscle relaxing effects
  • Anxiolytic effects
  • Enhancement of GABAergic neurotransmission
  • Modulation of GABA receptor affinity
  • Effect on serotonin
  • Suppression of paroxysmal activity

Dosage & Administration

  • Initial dose for adults with seizure disorders
  • Initial dose for adults with panic disorder
  • Dosing for pediatric patients
  • Dosing for infants and children
  • Intravenous injection dosage for infants, children, and adults

Interaction

  • No alteration of phenytoin, carbamazepine, or phenobarbital pharmacokinetics
  • Unknown effect on the metabolism of other drugs

Contraindications

  • Hypersensitivity to benzodiazepines
  • Clinical or biochemical evidence of significant liver disease
  • Acute narrow angle glaucoma

Side Effects

  • CNS depression
  • Drowsiness
  • Ataxia
  • Behavior problems
  • Abnormal eye movements
  • Aphonia
  • Tremor
  • Vertigo
  • Depression
  • Amnesia
  • Psychosis
  • Palpitations

Pregnancy & Lactation

  • Potential for producing congenital malformations
  • Administration only if benefits outweigh risks
  • Potential effects on newborns
  • Passage into maternal milk
  • Need for discontinuation of breastfeeding

Precautions & Warnings

  • Increased incidence of generalized tonic-clonic seizures in certain patients
  • Concomitant use with valproic acid
  • Special attention in infants and small children
  • Greater pharmacologic effects in elderly patients
  • Effect of renal impairment on pharmacokinetics
  • Difference in plasma protein binding in cirrhotic patients

Use in Special Populations

  • Increased production of saliva and bronchial secretion in infants and small children
  • Greater pharmacologic effects in elderly patients
  • No dose adjustment for renal impairment
  • Potential reduction in unbound Clonazepam clearance in liver cirrhosis

Overdose Effects

  • Common symptoms
  • Potential life-threatening effects if taken with other CNS depressants
  • Treatment involving monitoring and supportive measures
  • Prevention of further absorption using methods such as activated charcoal
  • Use of flumazenil as a benzodiazepine antagonist

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Benzodiazepine hypnotics

Reconstitution

  • Requirements for slow intravenous injection
  • Requirements for intravenous infusion
  • Use of intramuscular injection only in exceptional cases

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image

Common Questions about Cloma 1 mg Tablet

  • Administration as a sleeping pill
  • Duration of intake
  • Withdrawal symptoms
  • Early symptoms of suicidal thoughts
  • Effect on memory
  • Harmful effects of overdose
  • Co-administration with other drugs
  • Quick tips for use

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