Vcand 200 mg (Tablet)

Unit Price: ৳ 120.00 (2 x 6: ৳ 1,440.00)
Strip Price: ৳ 720.00

Medicine Details

Indications

  • Invasive aspergillosis
  • Candidemia
  • Disseminated candidiasis
  • Esophageal candidiasis
  • Scedosporium apiospermum infections
  • Fusarium species infections
  • Refraction to other therapy

Pharmacology

  • Triazole antifungal medication
  • Inhibition of ergosterol synthesis
  • Inhibition of CYP450-dependent 14-alpha sterol demethylase

Dosage & Administration

  • Oral administration
  • Loading dose regimen
  • Maintenance dose regimen
  • Injection administration
  • Different dosage for different conditions

Interaction

  • CYP3A4, CYP2C9 and CYP2C19 inhibitors and inducers
  • Increased concentrations and activity of drugs
  • Co-administration with Phenytoin or Efavirenz

Contraindications

  • Known hypersensitivity to Voriconazole
  • Co-administration with specific drugs
  • Risk of serious adverse reactions or loss of efficacy

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy if potential benefit justifies potential risk

Precautions & Warnings

  • Long term exposure requires careful assessment of benefit-risk balance
  • Squamous cell carcinoma of the skin reported with long-term treatment

Use in Special Populations

  • Efficacy to children under 12 years of age not established

Overdose Effects

  • No data found about overdose of Vcand

Therapeutic Class

  • Other Antifungal preparations

Reconstitution

  • Instructions for reconstituting suspension
  • Shake the bottle well before adding water
  • Discard suspension 14 days after reconstitution

Storage Conditions

  • Store in dry place
  • Store between 2°C to 8°C for powder
  • Store between 15°C to 30°C for reconstituted suspension

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