Ovenox 6000 Anti-Xa IU/0.6 ml (SC Injection)

0.6 ml pre-filled syringe: ৳ 651.95

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Synovia pharma plc
Also available as
Ovenox 2000 anti xa injection Ovenox 4000 anti xa injection Ovenox 8000 anti xa injection

Indications

  • Treatment of deep vein thrombosis
  • Treatment of pulmonary embolism
  • Treatment of unstable angina
  • Treatment of non-Q-wave myocardial infarction
  • Prevention of thrombus formation in haemodialysis
  • Prophylaxis of venous thromboembolic disease in surgical patients
  • Prophylaxis of venous thromboembolic disease in medical patients

Composition

  • Enoxaparin Sodium BP 20 mg
  • Enoxaparin Sodium BP 40 mg
  • Enoxaparin Sodium BP 60 mg
  • Enoxaparin Sodium BP 80 mg

Pharmacology

  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-IIa activity
  • Metabolised in the liver

Dosage

  • Subcutaneously 100 anti-Xa lU/kg twice daily for 10 days
  • Subcutaneously 150 anti-Xa lU/kg once daily for 10 days
  • Subcutaneously 100 anti-Xa lU/kg twice daily for 2-8 days
  • Subcutaneously 2000 anti-Xa IU once daily for 7-10 days
  • Subcutaneously 4000 anti-Xa IU once daily for 7-10 days

Administration

  • Subcutaneous injection
  • Injection site preparation
  • Selecting the dose
  • Injecting procedure
  • Disposal of used syringe

Interaction

  • Discontinuation of agents affecting hemostasis prior to Ovenox therapy
  • Careful clinical and laboratory monitoring

Contraindications

  • Hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain at injection sites
  • Skin rash at injection sites
  • Neuraxial hematomas

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of crossing the placental barrier
  • Use during pregnancy only if clearly needed
  • Unknown excretion in human milk
  • Consideration of nursing benefits

Precautions & Warnings

  • Injection route precautions
  • Caution in conditions with increased potential for bleeding
  • Measurement of platelet counts before treatment
  • Regular platelet count monitoring

Use in Special Populations

  • No dosage adjustment in elderly patients
  • Observation for signs of bleeding in patients with renal impairment
  • Caution in hepatically impaired patients

Overdose Effects

  • Hemorrhagic complications
  • Neutralization with protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Storage below 25°C
  • Keep out of the reach of children

Related Brands