Olmetab Plus 20 mg+12.5 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Olmesartan medoxomil hydrochlorothiazide |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Treatment of hypertension
Pharmacology
- Olmesartan is a reversible & competitive inhibitor of AT 1 receptor
- Hydrochlorothiazide affects renal tubular mechanisms of electrolyte reabsorption
Dosage & Administration
- Usual starting dose of 20/12.5 mg once daily
- May be titrated to two tablets 40/25 mg once daily
Interaction
- Olmesartan has no significant drug interactions reported
- Hydrochlorothiazide may interact with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, corticosteroids, ACTH, and lithium
Contraindications
- Hypersensitivity to any component of the product
- Anuria or hypersensitivity to sulfonamide-derived drugs
Side Effects
- Nausea
- Headache
- Dizziness
- Hyperuricemia
- Upper respiratory tract infection
- Urinary tract infection
- Chest pain
- Back pain
- Peripheral edema
- Abdominal pain
- Dyspepsia
- Gastroenteritis
- Diarrhea
Pregnancy & Lactation
- Safety and effectiveness not established, should be discontinued during pregnancy and lactation
Precautions & Warnings
- Periodic determination of serum electrolytes should be performed
- Hyperuricemia may occur in certain patients receiving thiazide therapy
- Impaired renal function
Use in Special Populations
- Not recommended for severe renal impairment
- No dosage adjustment needed for hepatic impairment
- Safety and effectiveness not established in pediatric patients
- Caution in selecting dose for elderly patients
Overdose Effects
- Olmesartan overdose may result in hypotension and tachycardia
- Hydrochlorothiazide overdose may lead to electrolyte depletion and dehydration
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store in a cool, dry place, protect from light and moisture, keep out of reach of children