Olmetab Plus 20 mg+12.5 mg (Tablet)

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)

Strip Price: ৳ 70.00

Medicine Details

Category	Details
Generic	Olmesartan medoxomil hydrochlorothiazide
Company	Ibn sina pharmaceuticals ltd
Also available as	Olmetab plus 40 mg tablet

Indications

Treatment of hypertension

Pharmacology

Olmesartan is a reversible & competitive inhibitor of AT 1 receptor
Hydrochlorothiazide affects renal tubular mechanisms of electrolyte reabsorption

Dosage & Administration

Usual starting dose of 20/12.5 mg once daily
May be titrated to two tablets 40/25 mg once daily

Interaction

Olmesartan has no significant drug interactions reported
Hydrochlorothiazide may interact with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, corticosteroids, ACTH, and lithium

Contraindications

Hypersensitivity to any component of the product
Anuria or hypersensitivity to sulfonamide-derived drugs

Side Effects

Nausea
Headache
Dizziness
Hyperuricemia
Upper respiratory tract infection
Urinary tract infection
Chest pain
Back pain
Peripheral edema
Abdominal pain
Dyspepsia
Gastroenteritis
Diarrhea

Pregnancy & Lactation

Safety and effectiveness not established, should be discontinued during pregnancy and lactation

Precautions & Warnings

Periodic determination of serum electrolytes should be performed
Hyperuricemia may occur in certain patients receiving thiazide therapy
Impaired renal function

Use in Special Populations

Not recommended for severe renal impairment
No dosage adjustment needed for hepatic impairment
Safety and effectiveness not established in pediatric patients
Caution in selecting dose for elderly patients

Overdose Effects

Olmesartan overdose may result in hypotension and tachycardia
Hydrochlorothiazide overdose may lead to electrolyte depletion and dehydration

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Store in a cool, dry place, protect from light and moisture, keep out of reach of children

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