Ovenox 8000 Anti-Xa IU/0.8 ml (SC Injection)

0.8 ml pre-filled syringe: ৳ 802.41

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Synovia pharma plc
Also available as
Ovenox 2000 anti xa injection Ovenox 4000 anti xa injection Ovenox 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in the extra-corporal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease
  • Prophylaxis of venous thromboembolic disease in bedridden medical patients

Composition

  • Enoxaparin Sodium BP 20 mg
  • Enoxaparin Sodium BP 40 mg
  • Enoxaparin Sodium BP 60 mg
  • Enoxaparin Sodium BP 80 mg

Pharmacology

  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-IIa activity
  • Metabolised in the liver

Dosage

  • Subcutaneously 100 anti-Xa lU/kg twice daily for 10 days
  • Subcutaneously 150 anti-Xa lU/kq once daily for 10 days
  • Subcutaneously 100 anti-Xa lU/kg for hemodialysis
  • Subcutaneously 2000 anti-Xa IU (0.2 ml) once daily for 7 to 10 days
  • Subcutaneously 4000 anti-Xa IU (0.4 ml) once daily for orthopedic surgery

Administration

  • Subcutaneous injection
  • Preparation of injection site on the stomach
  • Choosing injection area away from belly button
  • Disposal in sharps container

Interaction

  • Discontinuation of agents affecting hemostasis prior to Ovenox therapy
  • Careful clinical and laboratory monitoring for combination therapy

Contraindications

  • Hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage (bleeding)
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain and bluish marks at injection sites

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of crossing placental barrier
  • Caution for nursing mothers

Precautions & Warnings

  • Deep subcutaneous route for administration
  • Caution in conditions with increased potential for bleeding
  • Platelet count measurement before treatment initiation

Use in Special Populations

  • No dosage adjustment for elderly patients
  • Observation for signs and symptoms of bleeding in renal impairment
  • Caution in hepatically impaired patients

Overdose Effects

  • Hemorrhagic complications
  • Neutralization by protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Store in a cool and dry place
  • Protect from light and moisture
  • Do not store above 25°C

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