Deflaza 6 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 200.00

Medicine Details

Indications

  • Anaphylaxis
  • Asthma
  • Rheumatoid arthritis
  • Juvenile chronic arthritis
  • Polymyalgia rheumatica
  • Systemic lupus erythematosus
  • Dermatomyositis
  • Mixed connective tissue disease
  • Polyartritis nodosa
  • Sarcoidosis
  • Pemphigus
  • Bullous pemphigoid
  • Pyoderma gangrenosum
  • Minimal change nephrotic syndrome
  • Acute interstitial nephritis
  • Rheumatic carditis
  • Ulcerative colitis
  • Crohn's disease
  • Uveitis
  • Optic neuritis
  • Autoimmune haemolytic anaemia
  • Idiopathic thrombocytopenic purpura
  • Acute leukaemia
  • Lymphatic leukaemia
  • Malignant lymphoma
  • Multiple myeloma
  • Immune suppression in transplantation

Pharmacology

  • Anti-inflammatory action
  • Inhibition of Phospholipase A2 enzyme
  • Prostaglandin synthesis inhibition
  • Immunosuppressive action
  • Decrease of certain chemicals release

Dosage & Administration

  • Adult dosage range: 3-120 mg/day
  • Maintenance dose range in adults: 3-18 mg/day
  • Children dosage range: 0.25-1.5 mg/kg/day
  • Deflazacort withdrawal precautions

Interaction

  • Metabolism in the liver
  • Effects of liver enzyme inducers
  • Effects of liver enzyme inhibitors

Contraindications

  • Hypersensitivity to ingredients
  • Receiving live virus immunization

Side Effects

  • GI disturbances
  • Musculoskeletal issues
  • Endocrine issues
  • Neuropsychiatric issues
  • Ophthalmic issues
  • Fluid and electrolyte disturbances
  • Infection susceptibility
  • Impaired healing
  • Hypersensitivity reactions
  • Skin atrophy
  • Striae
  • Telangiectasia
  • Acne
  • Myocardial rupture
  • Thromboembolism

Pregnancy & Lactation

  • Placental crossing
  • Risk of intrauterine growth retardation
  • Corticosteroid excretion in breast milk
  • Adrenal suppression in infants

Precautions & Warnings

  • Cardiac diseases and heart failure
  • Hypertension
  • Thromboembolic disorders
  • Salt and water retention
  • Potassium excretion
  • Gastritis or oesophagitis
  • Diverticulitis
  • Ulcerative colitis
  • Diabetes mellitus
  • Osteoporosis
  • Myasthenia gravis
  • Renal insufficiency
  • Emotional instability
  • Psychotic tendency
  • Epilepsy
  • Corticosteroid-induced myopathy
  • Liver failure
  • Hypothyroidism
  • Cirrhosis
  • Ocular herpes simplex

Use in Special Populations

  • Hepatic Impairment precautions
  • Renal Impairment precautions
  • Elderly patient considerations

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Cool and dry storage below 25°C
  • Protection from light and moisture
  • Keep out of reach of children

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