Doxonil 100 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Medicon pharmaceuticals ltd |
| Also available as |
Title
Doxonil, Doxophylline Tablet
Categories
- Medicine
- Health & Wellness
- Bronchodilator
- Methyl Xanthine Derivatives
Description
Doxonil is used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with spastic bronchial component. It selectively inhibits phosphodiesterase 4, relaxes bronchial smooth muscle, and has decreased affinities toward adenosine A1 and A2 receptors. Dosage ranges from 200 mg for elderly to 400 mg for adults, with specific doses for children based on age and body weight. It should not be administered with other xanthine preparations, and caution is advised when combined with ephedrine or sympathomimetic drugs. Contraindicated in individuals with known hypersensitivity to the drug or xanthine derivatives, acute myocardial infarction, hypotension, and during lactation. Side effects may include nausea, vomiting, tachycardia, and insomnia, with potential overdose effects leading to severe cardiac arrhythmias and tonic-clonic seizures. It is contraindicated during lactation and should be used with caution in patients with cardiac disease, hypertension, severe hypoxemia, and renal impairment. The therapeutic class of the medicine is a bronchodilator and methyl xanthine derivatives, and it should be stored in a dry place away from light and heat, and out of the reach of children.
Dimensions
- N/A
Color options
- N/A
Functions
- Treats bronchial asthma
- Relaxes bronchial smooth muscle
- Inhibits phosphodiesterase 4
- Selectively inhibits adenosine A1 and A2 receptors
- Inhibits platelet activating factor (PAF) and generation of leukotriene production
Materials
- N/A
Technical specifications
- Tablet form
- Doxophylline active ingredient
Design elements
- N/A
Usability features
- Selectively inhibits adenosine A1 and A2 receptors
- Doxophylline SR tablet can be taken once daily if required daily dose is 400 mg
Age group
- Elderly
- Adults
- Children
Dosage instructions
- 200 mg tablet two or three times daily for elderly
- 400 mg tablet two or three times daily for adults
- Specific doses for children based on age and body weight
- Doxophylline SR tablet can be taken once daily for required daily dose of 400 mg
Interactions
- Should not be administered with other xanthine preparations
- Limit consumption of beverages and food containing caffeine
- Caution when combined with ephedrine or other sympathomimetic drugs
- Concurrent administration of certain drugs may reduce hepatic clearance of xanthine derivatives
- Phenytoin, other anticonvulsants, and cigarette smoking may increase clearance of xanthine derivatives
Contraindications
- Known hypersensitivity to the drug or xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side effects
- Nausea
- Vomiting
- Tachycardia
- Insomnia
- Hyperglycemia (rare cases)
- Albuminuria (rare cases)
- Severe cardiac arrhythmias (overdose)
- Tonic-clonic seizure (overdose)
Pregnancy lactation
- Contraindicated during lactation
- Use during pregnancy should be carefully evaluated based on risk-benefit ratio
- No sufficient clinical evidence about effects of the drug during pregnancy
Precautions warnings
- Caution in patients with cardiac disease
- Caution in patients with hypertension
- Caution in elderly patients
- Monitoring of blood levels may be necessary in certain conditions that influence the clearance of xanthine derivatives
Overdose effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Drug classes
- Bronchodilator
- Methyl xanthine derivatives
Storage conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children