Olpres A 5 mg+40 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
Treatment of hypertension alone or with other antihypertensive agents
Pharmacology
Amlodipine is a dihydropyridine calcium channel blocker, Olmesartan Medoxomil blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
Initial therapy with 5/20 mg once daily for 1 to 2 weeks, titrate as needed
Interaction
Antihypertensive effect may be attenuated by NSAIDs and selective COX-2 inhibitors
Contraindications
Cannot be co-administered with Aliskiren in patients with diabetes
Side Effects
Common side effects include peripheral edema, headache, flushing, dizziness, and sprue-like enteropathy
Pregnancy & Lactation
Pregnancy Category D, should not be used in 2nd and 3rd trimester, effect on human milk unknown
Precautions & Warnings
Risk for hypotension in volume- or salt-depleted patients, vasodilation in patients with severe aortic stenosis, increased frequency, duration or severity of angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
Pediatric use not established, no overall differences in safety or effectiveness in geriatric use, no studies in patients with renal impairment, initial therapy not recommended in hepatically impaired patients
Overdose Effects
No information on overdosage in humans
Therapeutic Class
Combined antihypertensive preparations
Storage Conditions
Do not store above 30°C, keep away from light and out of the reach of children