Olpres 10 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Olmesartan medoxomil |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- May be used alone or in combination with other antihypertensive agents
Pharmacology
- Blocks vasoconstrictor effects of angiotensin II
- Principal pressor agent of the renin-angiotensin system
- Stimulation of synthesis and release of aldosterone
- Cardiac stimulation and renal reabsorption of sodium
- Does not inhibit ACE (kininase II)
- Does not affect the response to bradykinin
- Inhibits negative regulatory feedback of angiotensin II on renin secretion
Dosage & Administration
- Usual recommended starting dose is 20 mg once daily
- May be increased to 40 mg for further reduction in blood pressure
- No advantage in twice-daily dosing over once daily
Interaction
- No significant drug interactions reported with digoxin or warfarin
- Bioavailability not significantly altered by antacids
- Not metabolized by the cytochrome P450 system
- Attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Well-tolerated with adverse reactions similar to placebo
- Frequency of adverse reactions not dose-related
- Most common adverse reaction: dizziness
Pregnancy & Lactation
- Discontinue product when pregnancy is detected
- Can cause injury or death to the developing fetus
Precautions & Warnings
- Changes in renal function may be anticipated in susceptible individuals
- Treatment associated with oliguria, progressive azotemia, acute renal failure, and death in some cases
Overdose Effects
- No experience of overdose reported
- Likely effects include hypotension and tachycardia
Therapeutic Class
- Angiotensin II receptor blocker
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C29H30N6O6
- Chemical Structure available
Common Questions
- Uses include treatment of high blood pressure
- Average time for peak effect is around 1 day to 1 week
- Frequency of usage is generally once or twice a day
- Advised to be consumed orally
- Storage should be at room temperature, away from heat and direct light
- Quick tips provided for taking the medication