Prebalin 150 mg (Capsule)

Unit Price: ৳ 30.20 (2 x 10: ৳ 604.00)
Strip Price: ৳ 302.00

Medicine Details

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)

Dosage

  • Maximum recommended dose for diabetic peripheral neuropathy: 100 mg three times a day (300 mg/day)
  • Recommended dose for postherpetic neuralgia: 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day)
  • Management of fibromyalgia: 300 to 450 mg/day
  • Recommended dose range for neuropathic pain associated with spinal cord injury: 150 to 600 mg/day

Administration

  • Route of administration: Oral route
  • Pregabalin CR tablet specific administration instructions: Administered after an evening meal, to be swallowed whole and not split, crushed or chewed

Interaction

  • Drug interaction with medication: Unlikely involvement in significant pharmacokinetic drug interactions.

Contraindications

Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Thinking abnormal (difficulty with concentration/attention)

Pregnancy & Lactation

  • Pregnancy: No adequate and well-controlled studies with pregabalin in pregnant women
  • Lactation: Small amounts of pregabalin detected in the milk of lactating women, not recommended during treatment

Precautions & Warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise
  • Immediate discontinuation if hypersensitivity reactions occur
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression may occur when used with concomitant CNS depressants
  • May cause dizziness and somnolence
  • Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
  • May cause peripheral edema
  • Cautious coadministration with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Use in children and adolescents: Safety and effectiveness not established for various conditions
  • Use in pediatric patients for the treatment of partial onset seizures: Safety and effectiveness not established for patients below the age of 1 month
  • Use of Prebalin extended-release tablet in pediatric patients: Safety and effectiveness not established

Overdose Effects

Symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block. No specific antidote available.

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Common Questions

  • What is Prebalin 150 mg Capsule?
  • How long do I need to use Prebalin 150 mg Capsule before I see improvement in my condition?
  • At what frequency do I need to use Prebalin 150 mg Capsule?
  • Should I use Prebalin 150 mg Capsule empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Prebalin 150 mg Capsule?
  • Does Prebalin 150 mg Capsule work in the same way for each disease?
  • How long do I need to take Prebalin 150 mg Capsule?
  • Is it necessary to continue taking Prebalin 150 mg Capsule even if I feel fine?
  • Can I take Diazepam and Prebalin 150 mg Capsule together?
  • Can the use of Prebalin 150 mg Capsule cause weight gain?
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