Rivo 0.25 mg (Tablet)
Unit Price: ৳ 3.50 (5 x 10: ৳ 175.00)
Strip Price: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | Orion pharma ltd |
| Also available as |
Title and Categories
- Rivo 0.25 mg Tablet
- Medicine
- Panic Disorder Treatment
- Antiepileptic Drug
- Benzodiazepine Hypnotic
Indications
- Treatment of panic disorder with or without agoraphobia
- Adjunct in the treatment of Lennox-Gastaut Syndrome
- Treatment of akinetic and myoclonic seizures
- Indicated for patients with absence seizures who have failed succinimides therapy
Pharmacology
- Exhibits anticonvulsive, sedative, muscle relaxing, and anxiolytic effects
- Enhances GABAergic neurotransmission at inhibitory synapses
- Shows effect on serotonin
- Rapidly suppresses various types of paroxysmal activity
Dosage & Administration
- Initial dose for adults with seizure disorders should not exceed 1.5 mg/day
- Initial dose for adults with panic disorder is 0.25 mg
- Pediatric dose based on body weight
- Dosage may be increased in increments every 3 days
- Different dosage for intravenous injection in infants, children, and adults
Interaction
- Does not alter the pharmacokinetics of phenytoin, carbamazepine, or phenobarbital
- Effect on the metabolism of other drugs has not been investigated
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Contraindicated in acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness in approximately 50% of patients
- Ataxia in approximately 30% of patients
- Behavior problems in approximately 25% of patients
- Other side effects such as abnormal eye movements, coma, tremor, vertigo, confusion, depression, increased libido, insomnia, psychosis, palpitations
Pregnancy & Lactation
- Potential teratogenic effects during pregnancy
- Use only if benefits outweigh the risks
- High doses in the last trimester can cause irregularities in the heartbeat of the unborn child
- Breastfeeding should be discontinued if the drug is administered
Precautions & Warnings
- May increase the incidence of generalized tonic-clonic seizures in patients with multiple seizure disorders
- Concomitant use with valproic acid may produce absence status
- Special considerations for pediatric, geriatric, renal impairment, and hepatic impairment use
Use in Special Populations
- May cause increased production of saliva and bronchial secretion in infants and small children
- Benzodiazepine pharmacologic effects appear to be greater in elderly patients
- Renal impairment does not affect pharmacokinetics
- Plasma protein binding in cirrhotic patients is significantly different
Overdose Effects
- Common symptoms include drowsiness, ataxia, dysarthria, and nystagmus
- May lead to areflexia, apnoea, hypotension, cardiorespiratory depression, and coma
- Increased frequency of seizures at supratherapeutic plasma concentrations
- Monitor vital signs and institute supportive measures
- Prevent further absorption using appropriate methods
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Instructions for slow intravenous injection, intravenous infusion, and intramuscular injection
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Chemical Structure Image
Common Questions
- Rivo 0.25 mg Tablet is not used as a sleeping pill
- Should be taken as long as the doctor has advised
- Common withdrawal symptoms include difficulty in sleeping, changes in mood, and increased sweating
- Pay attention to changes in mood, behaviors, thoughts, or feelings
- May cause weight gain and weight loss
- Does not affect memory
- Overdose can cause various symptoms
- Avoid combining with specific medications
- Quick tips for safe usage