Queta 25 mg (Tablet)

Unit Price: ৳ 3.00 (5 x 14: ৳ 210.00)

Strip Price: ৳ 42.00

Medicine Details

Category	Details
Generic	Quetiapine fumarate
Company	Opsonin pharma ltd
Also available as	Queta 100 mg tablet Queta xr 50 mg tablet Queta xr 200 mg tablet Queta xr 300 mg tablet

Belongs to dibenzothiazepine derivatives chemical class
Antagonist at serotonin 5HT1A and 5HT2 receptors
Antagonist at dopamine D1 and D2 receptors
Antagonist at histamine H1 receptors
Antagonist at adrenergic α1 and α2 receptors
No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
Mechanism of action is unknown
Efficacy in schizophrenia is mediated through dopamine D2 and serotonin 5HT2 antagonism
Antagonism of histamine H1 receptors may cause somnolence
Antagonism of adrenergic α receptors may cause orthostatic hypotension

Administered twice daily
First four days dosage titration
Dosage range of 300-450 mg/day for acute and chronic psychoses
Dosage range of 400-800 mg/day for manic episodes associated with bipolar disorder
Usual dose of 300 mg/day for depressive episodes associated with bipolar disorder
Total daily dose for the first four days of therapy
Can be titrated based on clinical response and tolerability
Maintenance therapy dosage adjustment based on clinical response

Caution with medicines causing electrolyte imbalance
Caution with medicines increasing QT interval
Co-administration with thioridazine or carbamazepine increases Quetiapine clearance
Co-administration with phenytoin increases Quetiapine clearance

Common adverse drug reactions include somnolence, dizziness, dry mouth, withdrawal symptoms, elevated serum triglyceride levels, elevated total cholesterol, decreased HDL cholesterol, weight gain, decreased haemoglobin, extrapyramidal symptoms

Safety and efficacy during human pregnancy not established
Use during pregnancy only if benefits justify potential risks
Administered dose and duration of treatment should be as low and short as possible
Excretion into human milk is unknown
Breast-feeding should be avoided while taking Quetiapine

Increased risk of suicidal thoughts, self-harm and suicide with depression
Caution in patients with known cardiovascular disease
Caution in patients with cerebrovascular disease
Caution in patients predisposed to hypotension
Caution in patients with a history of seizures
Consider dose reduction or discontinuation if signs of tardive dyskinesia appear
Discontinue in case of neuroleptic malignant syndrome
Exercise caution in patients with cardiovascular disease or family history of QT prolongation
Severe neutropenia uncommonly reported
Increases in blood glucose and hyperglycemia observed in clinical trials

Use with caution in the elderly
Slower dose titration and lower daily therapeutic dose may be needed in the elderly
Not indicated for use in children and adolescents below 18 years of age