Intravas 6000 Anti-Xa IU/0.6 ml (SC Injection)

0.6 ml pre-filled syringe: ৳ 600.00

Medicine Details

Indications

  • Treatment of deep vein thrombosis
  • Treatment of pulmonary embolism
  • Treatment of unstable angina
  • Treatment of non-Q-wave myocardial infarction
  • Prevention of thrombus formation in extra-corporeal circulation
  • Prophylaxis of venous thromboembolic disease in orthopedic surgery
  • Prophylaxis of venous thromboembolic disease in medical patients bedridden due to acute illness

Composition

  • Enoxaparin Sodium BP 20 mg
  • Enoxaparin Sodium BP 40 mg
  • Enoxaparin Sodium BP 60 mg
  • Enoxaparin Sodium BP 80 mg

Pharmacology

  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-IIa activity
  • Metabolized in the liver

Dosage

  • Subcutaneously 100 anti-Xa IU/kg
  • Subcutaneously 150 anti-Xa IU/kg
  • Subcutaneously 2000 anti-Xa IU
  • Oral anticoagulant therapy initiation

Administration

  • Injection site preparation
  • Selecting the dose
  • Injecting instructions
  • Disposal of used syringe

Interaction

  • Discontinuation of agents affecting hemostasis
  • Clinical and laboratory monitoring

Contraindications

  • Known hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain at injection sites
  • Skin rash at injection sites
  • Neuraxial hematomas

Pregnancy & Lactation

  • Pregnancy category B
  • Crosses placental barrier in humans
  • Potential for serious adverse reactions in nursing infants

Precautions & Warnings

  • Deep subcutaneous route administration
  • Caution in conditions with increased potential for bleeding
  • Platelet count measurement

Use in Special Populations

  • No dosage adjustment in elderly patients
  • Observation for signs and symptoms of bleeding in renal impairment

Overdose Effects

  • Hemorrhagic complications
  • Administration of protamine sulfate for neutralization

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Cool and dry place
  • Protection from light and moisture
  • Do not store above 25°C

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