Queta XR 200 mg (Tablet (Extended Release))
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of acute psychoses
- Treatment of chronic psychoses
- Treatment of schizophrenia
- Bipolar disorder treatment for manic episodes
- Bipolar disorder treatment for depressive episodes
- Maintenance treatment for bipolar I disorder
Pharmacology
- Atypical psychotropic agent
- Antagonist at neurotransmitter receptors
- Belongs to a chemical class - dibenzothiazepine derivatives
- Unknown mechanism of action
- Efficacy mediated through dopamine D2 antagonism
- Somnolence
- Orthostatic hypotension
Dosage & Administration
- Twice daily administration for acute and chronic psychoses
- Once or twice daily administration for bipolar disorder
- Titration for effective dose range
- Maintenance treatment adjustments
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration effects with thioridazine, carbamazepine, phenytoin
Contraindications
- Hypersensitivity to quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevated serum triglyceride levels
- Elevated total cholesterol levels
- Decreased HDL cholesterol
- Weight gain
- Orthostatic hypotension
- Extrapyramidal symptoms
Pregnancy & Lactation
- Use only if benefits justify potential risks during pregnancy
- Lowest possible dose and duration during pregnancy
- Avoid breastfeeding while taking quetiapine
Precautions & Warnings
- Risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular disease
- Caution in patients with cerebrovascular disease
- Caution in patients with conditions predisposing to hypotension
- Caution in patients with history of seizures
- Consideration of dose reduction for tardive dyskinesia
- Discontinuation in neuroleptic malignant syndrome
- Caution in patients with family history of QT prolongation
- Severe neutropenia reported in clinical trials
- Observation for hyperglycemia and diabetes mellitus
Use in Special Populations
- Caution in the elderly
- Slower rate of dose titration in the elderly
- Lower daily therapeutic dose in the elderly
- Not indicated for use in children and adolescents
Overdose Effects
- Reported survival in acute overdoses
- No specific antidote
- Consideration of multiple drug involvement
- Intensive care procedures recommended
- Support of the cardiovascular system
- Treatment of refractory hypotension
- Close medical supervision and monitoring
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of sight and reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light