Intravas 8000 Anti-Xa IU/0.8 ml (SC Injection)

0.8 ml pre-filled syringe: ৳ 650.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Aristopharma ltd
Also available as
Intravas 4000 anti xa injection Intravas 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis, with or without pulmonary embolism
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in the extra-corporal circulation during haemodialysis
  • Prophylaxis of venous thromboembolic disease in surgical patients
  • Prophylaxis of venous thromboembolic disease in medical patients

Composition

  • Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa IU
  • Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa IU

Pharmacology

  • Low molecular weight heparin
  • High anti-Xa activity
  • Low anti-lla or antithrombin activity
  • Metabolized in the liver

Dosage

  • Subcutaneously 100 anti-Xa lU/kg twice daily for 10 days
  • Subcutaneously 150 anti-Xa lU/kg once daily for 10 days
  • Subcutaneously 100 anti-Xa lU/kg twice daily for 2-8 days
  • Oral anticoagulant therapy initiation

Administration

  • Instructions on self-injection
  • Selecting dose based on body weight
  • Injecting into fatty tissue
  • Disposal of used syringe

Interaction

  • Discontinuation of agents affecting hemostasis prior to therapy
  • Careful clinical and laboratory monitoring

Contraindications

  • Known hypersensitivity to Enoxaparin Sodium
  • Active major bleeding
  • High risk of uncontrolled hemorrhage

Side Effects

  • Haemorrhage (bleeding)
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain at injection sites
  • Skin rash at injection sites
  • Neuraxial hematomas with concurrent use of spinal/epidural anesthesia

Pregnancy & Lactation

  • Pregnancy category B
  • No evidence of crossing placental barrier
  • Use during pregnancy only if clearly needed
  • Unknown excretion in human milk

Precautions & Warnings

  • Deep subcutaneous route for prophylactic and curative treatment
  • Caution in conditions with increased potential for bleeding
  • Platelet counts measurement before treatment initiation
  • Regular monitoring of platelet counts

Use in Special Populations

  • No dosage adjustment for elderly patients
  • Observation for signs and symptoms of bleeding in renal impairment
  • Caution in hepatically impaired patients

Overdose Effects

  • Hemorrhagic complications
  • Neutralization by slow i.v. injection of protamine sulfate

Therapeutic Class

  • Parenteral anti-coagulants

Storage Conditions

  • Store in a cool and dry place
  • Protect from light and moisture
  • Do not store above 25°C
  • Keep out of the reach of children

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