Vefend 50 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by specific fungal species
- Use in patients intolerant of or refractory to other therapy
- Indicated for patients 12 years of age and older
Pharmacology
- Triazole antifungal medication
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration with or without a meal
- Different loading and maintenance dosages based on body weight
- Injection dosage for various fungal infections
Interaction
- Interacts with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- May affect concentrations and activity of other drugs
Contraindications
- Hypersensitivity to voriconazole or any components
- Co-administration with specific drugs due to risk of serious adverse reactions
- Co-administration with certain drugs due to risk of loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy if potential benefit justifies potential risk
- No specific information about lactation
Precautions & Warnings
- Long-term exposure requires careful benefit-risk assessment
- Reports of squamous cell carcinoma of the skin (SCC) with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No specific data available about overdose effects
Therapeutic Class
- Belongs to the category of Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
Storage Conditions
- Store in a dry place below 25°C temperature and protected from light
- Store suspension between 2°C to 8°C temperature
- Discard reconstituted suspension after 14 days