Vefend 50 mg (Tablet)

Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00

Medicine Details

Category Details
Generic Voriconazole
Company Acme laboratories ltd
Also available as

Indications

  • Treatment of invasive aspergillosis
  • Treatment of candidemia and disseminated candidiasis
  • Treatment of esophageal candidiasis
  • Treatment of serious infections caused by specific fungal species
  • Use in patients intolerant of or refractory to other therapy
  • Indicated for patients 12 years of age and older

Pharmacology

  • Triazole antifungal medication
  • Binds and inhibits ergosterol synthesis
  • Inhibits CYP450-dependent 14-alpha sterol demethylase
  • Results in depletion of ergosterol in fungal cell membrane

Dosage & Administration

  • Oral administration with or without a meal
  • Different loading and maintenance dosages based on body weight
  • Injection dosage for various fungal infections

Interaction

  • Interacts with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
  • May affect concentrations and activity of other drugs

Contraindications

  • Hypersensitivity to voriconazole or any components
  • Co-administration with specific drugs due to risk of serious adverse reactions
  • Co-administration with certain drugs due to risk of loss of efficacy

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during pregnancy if potential benefit justifies potential risk
  • No specific information about lactation

Precautions & Warnings

  • Long-term exposure requires careful benefit-risk assessment
  • Reports of squamous cell carcinoma of the skin (SCC) with long-term treatment

Use in Special Populations

  • Efficacy not established in children under 12 years of age

Overdose Effects

  • No specific data available about overdose effects

Therapeutic Class

  • Belongs to the category of Other Antifungal preparations

Reconstitution

  • Instructions for reconstituting suspension

Storage Conditions

  • Store in a dry place below 25°C temperature and protected from light
  • Store suspension between 2°C to 8°C temperature
  • Discard reconstituted suspension after 14 days

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